Title: Myocardial infarction without obstructive coronary artery disease<br/>Author: Semhar Tewelde<br/><a href='http://umem.org/profiles/faculty/352/'>[Click to email author]</a><hr/><p>
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MI without obstructive CAD is common, occurring in 5–10% of patients w/woman most commonly affected</li>
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Mechanisms for MI without obstructive CAD include vasospasm, embolism, myocarditis, dissection, tako-tsubo, and occult plaque rupture</li>
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Recent studies have applied cardiac MRI (CMR) with intravascular ultrasound (IVUS) to determine the mechanism of MI without obstructive CAD</li>
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In this study plaque disruption frequently occurred when the angiogram was normal or showed minimal atherosclerosis; Plaque rupture was demonstrated on IVUS in ~40% of women studied</li>
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IVUS and CMR identified the potential mechanism of MI in 70%</li>
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Consider theses adjunctive tools in the assessment of all patients with a clinical syndrome of MI who do not have obstructive CAD at angiography</li>
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<fieldset><legend>References</legend>
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Reynolds H. Myocardial infarction without obstructive coronary artery disease. Curr Opin Cardiol 2012, 27:655–660</p>
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