Title: Statin Therapy on Intracoronary Plaque<br/>Author: Semhar Tewelde<br/><a href='http://umem.org/profiles/faculty/352/'>[Click to email author]</a><hr/><ul>
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Statin therapy significantly reduces the risk for thrombotic events</li>
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A recent study sought to determine the impact of short-term intensive statin therapy on intracoronary plaque lipid content</li>
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87 patients with multivessel CAD undergoing percutaneous coronary intervention and at least 1 other severely obstructive were randomized to intensive (rosuvastatin</div>
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40 mg daily) or standard-of-care lipid-lowering therapy</div>
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Upon follow-up, median reduction (95% confidence interval) was significantly greater in the intensive versus standard group (p=0.01)</li>
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Short-term intensive statin therapy in small trials reduces lipid content in obstructive lesions and further large studies with longer follow-up are warranted</li>
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<fieldset><legend>References</legend>
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Kini A, Baber U, et al. Changes in Plaque Lipid Content After Short-Term Intensive Versus Standard Statin Therapy. JACC. Vol. 62, No. 1, 2013</p>
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