Title: Bad brain, good lungs.... Right?<br/>Author: John Greenwood<br/><a href='http://umem.org/profiles/faculty/412/'>[Click to email author]</a><hr/><p>
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<strong><u>Bad brain, good lungs.... Right?</u></strong></p>
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A recent retrospective study reviewed the incidence of acute respiratory distress syndrome (ARDS) in patients presenting with spontaneous intracerebral hemorrhage over a 10-year period. After reviewing 1,665 patients, the authors found that:</p>
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The development of ARDS occurred in approximately 27% of patients with spontaneous ICH (similiar to previous literature).</li>
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The incidence ARDS after spontaneous ICH was similiar to other "high-risk" conditions such as sepsis, trauma, & aspiration.</li>
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<strong>Modifiable risk factors include: high tidal volume ventilation, higher total fluid balance, & transfusion of PRBCs/FFP.</strong><br />
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It's of particular importance to note that <em>high tidal volume ventilation (>8cc/kg) was the single greatest modifiable factor for the development of ARDS.</em></p>
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<strong><u>Bottom line</u>: Try and use lung-protective ventilation strategies (6-8cc/kg <em>ideal</em> <em>body weight</em>) and avoid excessive volume resuscitation in your critically-ill patients whenever possible. Even in cases of isolated intracerebral hemorrhage - where the patient's lungs may appear to be <em>completely</em> normal - traditional tidal volume settings may be harmful.</strong></p>
<fieldset><legend>References</legend>
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Elmer J, Hou P, Wilcox SR, et al. Acute respiratory distress syndrome after spontaneous intracerebral hemorrhage. <em>Crit Care Med;</em> 2013 Aug; 41(8): 1992-2001.</li>
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