Title: Tranexamic Acid in Anterior Epistaxis<br/>Author: Ellen Lemkin<br/><a href='http://umem.org/profiles/faculty/182/'>[Click to email author]</a><hr/><p>
        Tranexamic Acid (TXA) topically applied was compared to anterior nasal packing in 216 patients with acute anterior epistaxis. Cotton pledgets (15 cm) soaked in injectable TXA (500 mg/5 ml) were inserted into the bleeding nostril and removed after bleeding had arrested. This was compared to standard anterior packing.</p>
<p>
        RESULTS</p>
<table border="1" cellpadding="0" cellspacing="0">
        <tbody>
                <tr>
                        <td style="width:590px;">
                                <p>
                                                                                                           TXA            Anterior packing</p>
                        </td>
                </tr>
                <tr>
                        <td style="width:590px;">
                                <p>
                                        % pts bleeding stopped in 10 min:           71%           31.2%                </p>
                        </td>
                </tr>
                <tr>
                        <td style="width:590px;">
                                <p>
                                        Discharge after 2 hours                           95.3%           6.4%</p>
                        </td>
                </tr>
                <tr>
                        <td style="width:590px;">
                                <p>
                                        Rebleeding in 24 h hours                          4.7%        11%</p>
                        </td>
                </tr>
                <tr>
                        <td style="width:590px;">
                                <p>
                                        Satisfaction scores                                    8.5               4.4</p>
                        </td>
                </tr>
        </tbody>
</table>
<p>
         </p>
<p>
        <span style="font-size:14px;"><strong>Bottom line: topical tranexamic acid looks promising for control of uncomplicated anterior epistaxis.</strong></span></p>
<fieldset><legend>References</legend>

                <p>
        Zahed R, Moharamzadeh P, AlizadeArasi S, Ghasemi A, Saeedi M. A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial. AJEM 2013 (31):1389-92.</p>
</fieldset>