Title: Cardiovascular Morbidity & Sleep Apnea<br/>Author: Semhar Tewelde<br/><a href='http://umem.org/profiles/faculty/352/'>[Click to email author]</a><hr/><p>
<strong><u>Cardiovascular Morbidity & Sleep Apnea</u></strong></p>
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Obstructive sleep apnea (OSA) is characterized by sleep-related periodic breathing, upper-airway obstruction, sleep disruption, and hemodynamic perturbations</p>
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Epidemiological data shows a strong association between untreated OSA & cardiovascular morbidity/mortality</p>
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Two recent studies by Gottlieb et al. (1) & Chirinos et al. (2) elucidated two important explicit and complicit treatment considerations for OSA</p>
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(1) In moderate-to-severe obstructive sleep apnea, the use of CPAP alone during sleep may ameliorate systemic hypertension and cardiovascular risk, even in patients who do not have "subjective" sleepiness</p>
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(2) Weight loss combined with CPAP use may further decrease cardiovascular morbidity </p>
<fieldset><legend>References</legend>
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Basner R. Cardiovascular Morbidity and Obstructive Sleep Apnea. N Engl J Med 2014; 370:2339-2341 <a href="http://www.nejm.org.proxy-hs.researchport.umd.edu/toc/nejm/370/24/">June 12, 2014</a></p>
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