Title: The Role of the CVP in a Post- "7 Mares" Era<br/>Author: John Greenwood<br/><a href='http://umem.org/profiles/alumni/412/'>[Click to email author]</a><hr/><p>
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<u><strong>The Role of the CVP in a Post- “7 Mares” Era</strong></u><br />
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The role for using central venous pressure (CVP) as a measure of volume responsiveness has largely fallen out of favor over the years.<sup>1</sup> There are certainly better indices for fluid responsiveness, but don’t be fooled – the CVP isn’t a one trick pony. In fact, a high or rapidly rising CVP should raise a significant concern for impending cardiovascular collapse.</p>
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Consider the following differential diagnosis in the patient with an abnormally high or rising CVP ( >10 cm H<sub>2</sub>O).</p>
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Excessive pressures outside of the heart or impediments to venous return (<em>juxta-cardiac</em> pressures)
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Cardiac tamponade</li>
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Auto PEEP or breath stacking during mechanical ventilation</li>
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Tension pneumothorax</li>
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Venous return that’s more than the right ventricle can handle
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RV failure</li>
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Severe tricuspid valve disease</li>
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Massive increase in pulmonary vascular resistance (massive PE, pulmonary hypertension, ARDS, LV failure)</li>
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<strong>Bottom Line: In a time where the utility of the CVP has been largely dismissed, remember that an abnormal CVP offers great deal of information beyond a simple measure of volume status.</strong></p>
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<u><strong>References</strong></u></p>
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Marik PE, Baram M, Vahid B. Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares. <em>Chest</em>. 2008;134(1):172-8.</li>
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Berlin DA, Bakker J. Starling curves and central venous pressure. <em>Critical Care. </em>2015;19(1):55.</li>
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