Title: Post-arrest therapeutic hypothermia in children?<br/>Author: Rose Chasm<br/><a href='http://umem.org/profiles/faculty/82/'>[Click to email author]</a><hr/><ul>
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Evidence-based guidelines recommend therapeutic hypothermia in adults following resuscitation from cardiac arrest.</li>
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Very few trials exist for children.</li>
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The most recently published study on the subject (New England Journal of Medicine, May 2015) was of 295 children aged 2 days to 18 years old, at 38 different childrens hospitals who underwent targeted temperature management. </li>
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There was no significant difference in primary outcome between the hypothermia and normothermia groups. One year survival and 28-day survival were similar, as were incidences of infection, serious arrhythmias, and use of blood products.</li>
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"<strong>In comotose children who survived out-of-hospital cardiac arrest, therapeutic hypothermia, as compared with therapeutic normothermia , did not confer a significant benefit in survival with a good functional outcome at 1 year."</strong></li>
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<fieldset><legend>References</legend>
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Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest in Children. Mosler FW, et al. N Eng J Med 2015; 372:1898-1908. May 2015</p>
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