Title: When to stop antibiotics in the ICU?<br/>Author: Feras Khan<br/><a href='http://umem.org/profiles/faculty/1145/'>[Click to email author]</a><hr/><p>
Happy New Year!!!</p>
<p>
My new year's resolution is to use less antibiotics (and eat more Cap'n Crunch Berries) </p>
<p>
Will I be successful?</p>
<p>
A multi-center, ICU, observational study looking at over 900 patients from 67 ICUs showed that half of all empiric antibiotics ordered in patients are continued for at least 72 hours in the abscence of adjudicated infection. </p>
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<li>
We have been well trained to start antibiotics but stopping or limiting use can be difficult</li>
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The greater the severity of illness, the longer the antibiotics were continued in this study</li>
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<span style="background-color:#ffff00;">Things to consider: </span></p>
<p>
The same way we try and limit central line use, we should try and decrease antibiotic usage on a daily basis</p>
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<u>Tips to decrease use:</u> daily clinical pharmacist input, ID specialist involvement, automated stop dates, 72 hour vancomycin cessation protocols, incentives for de-escalation, educational resources</p>
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</p>
<fieldset><legend>References</legend>
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Critical Care Medicine:</div>
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<a href="http://journals.lww.com/ccmjournal/toc/2015/12000" style="color: rgb(59, 75, 107);">December 2015 - Volume 43 - Issue 12 - p 2527–2534</a></div>
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doi: 10.1097/CCM.0000000000001294</div>
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Feature Article</div>
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A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States</h2>
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Thomas, Zachariah PharmD</p>
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