Title: Urinary Tract Infection Pathogens in Infants<br/>Author: Jenny Guyther<br/><a href='http://umem.org/profiles/faculty/314/'>[Click to email author]</a><hr/><p>
There is not much data published on susceptabilities of urinary pathogens in infants. What resistance patterns are seen in infants < 2 months in gram negative uropathogens?</p>
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A retrospective study of previously healthy infants diagnosed with urinary tract infections in Jerusalem over a 6 year period examined this question. The standard treatment at this hospital included ampicillin and gentamycin for less than 1 month olds and ampicillin or cefuroxime for 1-2 month olds.</p>
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306 UTIs were diagnosed</p>
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74% were resistant to ampicillin</p>
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22% were resistant to cefazolin and augmentin</p>
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8% were resistant to cefuroxime</p>
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7% were resistant to gentamycin</p>
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<span style="font-family: arial, sans-serif; font-size: 12.8px;">Of the organisms cultured, 76% were E. coli and 14% were Klebsiella.</span></p>
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<span style="font-family: arial, sans-serif; font-size: 12.8px;">Bottom line: Know your local resistance patterns.</span></p>
<fieldset><legend>References</legend>
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<span style="font-family: arial, sans-serif; font-size: 12.8px;">Segal Z et al. Infants under two months of age with urinary tract infections are showing increasing resistance to empirical and oral antibiotics. Acta Paediatrica. Dec 2015. Epub ahead of print.</span></p>
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