Title: Refractory Status Epilepticus<br/>Author: Mike Winters<br/><a href='http://umem.org/profiles/faculty/141/'>[Click to email author]</a><hr/><p> <strong><u>Ketamine for RSE?</u></strong></p> <ul> <li> Up to 43% of patients with status epilepticus may progress to refractory status epilepticus (RSE).</li> <li> Propofol, midazolam, and barbituates are often recommended for patients with RSE.</li> <li> Importantly, all of these medications may be limited by hypotension and respiratory depression.</li> <li> Ketamine is emerging as adjuvant therapy for patients with RSE.</li> <li> The loading dose of ketamine ranges from 0.5 to 3 mg/kg, followed by a maintenance infusion of 0.3 to 4 mg/kg/h.</li> </ul> <fieldset><legend>References</legend>
<p> Legriel S, et al. What's new in refractory status epilepticus? <em>Intensive Care Med</em> 2016. [Epub ahead of print]</p> </fieldset>