Title: Viscosupplementation<br/>Author: Brian Corwell<br/><a href='http://umem.org/profiles/faculty/294/'>[Click to email author]</a><hr/><p>
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<span style="font-size:14px;"><strong>Viscosupplementation</strong></span></p>
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Hyaluronic acid (HA) is a high-molecular weight polysaccharide</p>
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A major component of synovial fluid and of cartilage</p>
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Major role of HA is as a lubricant, shock absorption, antinociceptive effect</p>
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Used in veterinary medicine for decades</p>
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Multiple brands exist with differences based on the molecular weight and how they are produced</p>
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Use supported by the Cochrane database (2007, 2014) for knee OA</p>
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Post injection strength gains are due to pain relief</p>
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May have a role for those who cannot receive steroid injections</p>
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Inject in similar manner to intra articular steroids</p>
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Caution in those with known allergy to poultry /eggs</p>
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Risks: Local reaction (likely from preservative), injection site pain, infection, bleeding.</p>