Title: Reversible Cerebral Vasoconstriction Syndrome (RCVS)<br/>Author: WanTsu Wendy Chang<br/><a href='http://umem.org/profiles/faculty/1322/'>[Click to email author]</a><hr/><p>
<!--?xml version="1.0" encoding="UTF-8" standalone="no"?--></p>
<ul>
<li>
<span style="font-size:16px;">Reversible cerebral vasoconstriction syndrome (RCVS) is the <em><strong>second most common</strong></em> cause of thunderclap headache after aneurysmal subarachnoid hemorrhage (SAH) and the <em><strong>most common</strong></em> cause of recurrent thunderclap headaches.</span></li>
<li>
<span style="font-size:16px;"><strong><em>Up to 40% of patients with RCVS have a history of migraine</em>.</strong></span></li>
<li>
<span style="font-size:16px;">It is associated with selective serotonin reuptake inhibitors (SSRIs), triptans, cocaine, marijuana, tacrolimus, oral contraceptives, as well as the peripartum period.</span></li>
<li>
<span style="font-size:16px;">Symptoms are often triggered by emotional stress, sexual activity, showering, straining, and physical exertion.</span></li>
<li>
<span style="font-size:16px;">Although the vasoconstriction is reversible, it can cause <em><strong>intracranial hemorrhage, seizures, stroke, and coma</strong></em>.</span></li>
<li>
<span style="font-size:16px;">Diagnosis is by history, cerebral angiography and exclusion of aneurysmal SAH.</span></li>
</ul>
<p>
<span style="font-size:16px;"><strong><u>Bottom Line</u>:</strong> Consider RCVS in the differential of thunderclap headache and in patients who present with worse than usual migraine headache.</span></p>
<fieldset><legend>References</legend>
<p>
<!--?xml version="1.0" encoding="UTF-8" standalone="no"?-->Arrigan MT, Heran MKS, Shewchuk JR. Reversible cerebral vasoconstriction syndrome: an important and common cause of thunderclap and recurrent headaches. <em>Clin Radiol</em>. 2017 Dec 21 [Epub ahead of print]</p>
<p style="text-align: center;">
<strong><em>Follow me on Twitter @EM_NCC</em></strong></p>
</fieldset>