Title: Influenza -- critical care considerations<br/>Author: Daniel Haase<br/><a href='http://umem.org/profiles/faculty/1447/'>[Click to email author]</a><hr/><p>
--Influenza activity (mainly H3N2) remains wide spread across the US with activity continuing to increase (for the week ending on February 3, 2018)</p>
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<u>A few critical care considerations/recommendations from the CDC:</u></p>
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1. Oseltamivir remains the recommended drug in critically ill patients</p>
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2. Treatment up to 4 or 5 days after symptom onset may decrease risk of severe outcomes in hospitalized patients</p>
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3. Limited data to support high dose oseltamivir in immunocompromised and critically ill, though little down side in patient with normal renal function</p>
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4. Consider longer duration of treatment in immunosuppressed and critically ill patients. Use PCR and clinical judgement to guide</p>
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***Also, remember "rapid flu" test is only ~62% sensitive! Do not rely on a rapid flu to "rule out" the diagnosis. PCR is the test of choice.</p>
<fieldset><legend>References</legend>
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https://www.cdc.gov/flu/pdf/professionals/antivirals/antiviral-summary-clinician.pdf OR </p>
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https://www.cdc.gov/flu/professionals/antivirals/summary-clinicians.htm</p>
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to reference original articles and full CDC recommendations</p>
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