Title: Toxin-induced nystagmus<br/>Author: Hong Kim<br/><a href='http://umem.org/profiles/faculty/526/'>[Click to email author]</a><hr/><p> Abnormal ocular movement (e.g. nystagmus) can often be observed in select CNS pathology.</p> <p> Certain drugs/toxin overdose can also induce nystagmus.</p> <ul> <li> Anti-epileptics: carbamazepine, lamotrigine, topiramate, phenytoin</li> <li> Ethanol</li> <li> Ketamine, phencyclidine (PCP), dextromethorphan – vertical or rotary nystagmus</li> <li> Serotonergic syndrome/5-HT agonists – opsoclonus</li> <li> Monoamine oxidase inhibitors – ping-pong nystagmus</li> <li> Lithium</li> <li> Scorpion envenomation </li> </ul> <p> In an "unknown" intoxication, physical exam findings such as nystagmus may help narrow the identity of the suspected ingestion/overdose.</p>