Title: Does LR Increase Serum Lactate?<br/>Author: Mike Winters<br/><a href='http://umem.org/profiles/faculty/141/'>[Click to email author]</a><hr/><p> <strong><u>Does Lactated Ringer's Raise Serum Lactate?</u></strong></p> <ul> <li> Intravenous fluid administration is a cornerstone of resuscitation and the treatment of many critically ill ED patients.</li> <li> Recent publications have suggested that balanced crystalloid solutions may be better than 0.9% normal saline (NS) for select conditions.</li> <li> Lactated Ringer's (LR) is a common balanced crystalloid solution often used for fluid resuscitation in critically ill patients.</li> <li> AS LR contains approximately 28 mmol/L of sodium lactate, the question of whether LR elevates serum lacate is frequently asked.</li> <li> In a recent small, randomized, double-blind, controlled trial, investigators randomized healthy volunteers to receive 30 ml/kg of either 0.9% NS or LR. The authors report no statistical difference in the mean serum lactate when comparing LR to 0.9% NS.</li> </ul> <fieldset><legend>References</legend>
<p> Zitek T, et al. Does intraveneous lactated ringer's solution raise serum lactate? <em>J Emerg Med.</em> 2018; 55:313-8.</p> </fieldset>