Title: Capillary Refill vs. Lactate in Septic Shock<br/>Author: Mark Sutherland<br/><a href='http://umem.org/profiles/resident/1396/'>[Click to email author]</a><hr/><div>
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ANDROMEDA-SHOCK compared using capillary refill time versus lactate clearance as a guide for resuscitation in septic shock patients</li>
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The cap refill group showed better SOFA scores at 72 hours, and a trend to lower mortality</li>
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In the study, cap refill was performed by pressing a glass microscope slide to the ventral surface of the second finger distal phalanx, holding until blanched for 10 seconds, and releasing. Cap refill > 3 seconds was considered abnormal.</li>
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<strong>Bottom Line</strong>: Consider using capillary refill as an alternate (or complimentary) endpoint to lactate clearance when resuscitating your septic shock patients.</p>
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<fieldset><legend>References</legend>
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Hernández G, Ospina-Tascón GA, Damiani LP, et al. Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. JAMA. 2019;321(7):654–664. doi:10.1001/jama.2019.0071</p>
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Andromeda-shock - Capillary Refill Vs. Lactate. Clay Smith - https://journalfeed.org/article-a-day/2019/andromeda-shock-rct-perfusion-vs-lactate</p>
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