Title: Increasing gabapentin misuse and intentional (self-harm) exposure in the U.S.<br/>Author: Hong Kim<br/><a href='http://umem.org/profiles/faculty/526/'>[Click to email author]</a><hr/><p>
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Non-opioid medications such as gabapentin are frequently prescribed for the management of pain. </p>
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A retrospective study of the National Poison Data System (data collected by the U.S. Poison Centers) from 2013 – 2017 showed increasing trend of gabapentin exposure.</p>
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Gabapentin exposure increased between 2013 and 2017 by:</p>
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Total exposure: 72.3% </li>
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Isolated intentional suicide attempt: 80.5%</li>
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Isolated exposure: 67.1%</li>
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Isolated intentional abuse/misuse: 119.9%</li>
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5 most commonly co-ingested substances with gabapentin</p>
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Sedative-hypnotic: 22.9%</li>
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Antidepressant: 12.7%</li>
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Antihypertensive: 9.9%</li>
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Opioid: 9.0%</li>
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Antipsychotics: 6.3%</li>
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16.7% of the isolated gabapentin exposure required hospitalization.</p>
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Conclusion:</p>
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Gabapentin abuse/misuse and ingestion with self-harm intent is increasing in the U.S.</li>
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