Title: Predictors of fatality from intentional drug overdose<br/>Author: Hong Kim<br/><a href='http://umem.org/profiles/faculty/526/'>[Click to email author]</a><hr/><p>
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Intentional drug overdose (IDO) can lead to significant morbidity and can increased patient's risk of death. A study was recently performed to identify the predictors of death in a cohort of patient who intentionally overdose on drug(s). </p>
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National Self-Harm Registry and National Drug-Related Death Index were reviewed (between January 1<sup>st</sup>, 2007 and December 31<sup>st</sup>, 2014) to identify the study cohort.</p>
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<strong>Results</strong></p>
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Non fatal IDO</p>
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Fatal IDO</p>
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Number of cases</p>
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63,831</p>
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364</p>
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Incidence </p>
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148.8/100,000</p>
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1.01/100,000</p>
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Male</p>
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42.0%</p>
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55.2%</p>
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Age, years (median)</p>
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35</p>
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44</p>
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Multiple drug ingestion</p>
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48.5%</p>
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78.3%</p>
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Risk of death</p>
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1.7 times higher in MALE compared to female</li>
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5 times higher in age > 45 years vs. 15-24 years</li>
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3 times higher in patient who ingested 2 – 5 distinct agents, 6x higher in > 6 agent vs. single agent</li>
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15 times higher after TCA ingestion</li>
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12 times higher after opioids ingestion</li>
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4 times higher after antidepressants or illicit substance ingestion/exposure</li>
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<strong>Conclusion</strong></p>
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Older age (> 45 years), male gender and ingestion of multiple agents (>2) were associated with higher risk of death from intention drug overdose.</li>
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<fieldset><legend>References</legend>
<p>
<span .="" a="" android="" apple="" case="" color="" d.="" drugs="" e.="" fatality="" i="" i.="" in="" intentional="" national="" of="" r.="" segoe="" study="" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-size: 16px; font-family: Calibri, Helvetica, sans-serif, EmojiFont, " taken="" ui="">International <span class="il">Journal</span> of Drug Policy<span android="" apple="" color="" i="" segoe="" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-size: 16px; font-family: Calibri, Helvetica, sans-serif, EmojiFont, " ui="">76<span a="" android="" apple="" color="" data-saferedirecturl="https://www.google.com/url?q=https://doi.org/10.1016/j.drugpo.2019.102609&source=gmail&ust=1579912507673000&usg=AFQjCNE3zqffjOoWHfASFVTpJE89faMVVA" href="https://doi.org/10.1016/j.drugpo.2019.102609" id="m_6020739822714105108LPlnk451186" segoe="" style="font-size: 16px; color: rgb(17, 85, 204); font-family: Calibri, Helvetica, sans-serif, EmojiFont, " target="_blank" ui="">https://doi.org/10.<wbr />1016/j.drugpo.2019.102609</span></span></span></p>
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