Title: Epinephrine administration in pediatric prehospital cardiac arrest<br/>Author: Jenny Guyther<br/><a href='http://umem.org/profiles/faculty/314/'>[Click to email author]</a><hr/><div style="font-family: Arial, Helvetica, sans-serif; font-size: small;">
This was a population based observational study in Japan that enrolled pediatric patients age <strong>8-17 years </strong>with out-of-hospital cardiac arrests (OHCA). The primary end point was 1 month survival and secondary end points were favorable 1 month neurological outcomes and pre-hospital return of spontaneous circulation (ROSC). In Japan, prehospital administration of epinephrine is allowed in children 8 years and older with appropriate training.</div>
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3961 pediatric OHCA were eligible (306 received epinephrine and 3655 patients did not).</div>
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There were no differences between the epinephrine and no epinephrine groups in regards to 1 month survival or favorable neurological outcome. The epinephrine group had a slightly higher likelihood of achieving pre-hospital ROSC.</div>
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<span style="font-family: Arial, Helvetica, sans-serif; font-size: small;">Matsuyama et al. Pre-Hospital Administration of Epinephrine in Pediatric Patients with Out-of-Hospital Cardiac Arrests. JACC: 75 (2); 2020.</span></p>
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