Title: The Rising Incidence of Cerebral Venous Thrombosis <br/>Author: WanTsu Wendy Chang<br/><a href='http://umem.org/profiles/faculty/1322/'>[Click to email author]</a><hr/><div class="ListContainerWrapper SCXW19586824 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; position: relative; color: rgb(0, 0, 0); font-size: 14.6667px;">
<div class="OutlineElement Ltr BCX0 SCXW27791880 Paragraph SCXW19586824 BCX0 OutlineElement Ltr BCX0 SCXW19586824" style="display: block; font-size: 11pt; overflow-wrap: break-word; vertical-align: baseline; background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; overflow: visible; cursor: text; clear: both; position: relative; direction: ltr;">
<ul>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;"><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">Cerebral venous thrombosis (CVT) is thought to predominantly affect young and middle-aged females.</span><span class="EOP SCXW27791880 BCX0" data-ccp-props="{" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; line-height: 19.425px;"> </span></span>
<ul>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;">Known r<span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">isk factors include prothrombotic states such as malignancy</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"> and</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"> oral contraceptive use, as well as local infections and head trauma.</span></span></li>
</ul>
</li>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;">The i<span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">ncidence of stroke in young adults is rising </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">worldwide.</span></span></li>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;">A r<span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">ecent study by </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"><span 1px="" background-color:="" border-bottom:="" class="NormalTextRun SpellingErrorV2 SCXW27791880 BCX0" data:image="" solid="" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; background-repeat: repeat-x; background-position: left bottom; background-image: url(">Otite</span></span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"> <em>et al</em>. examined the incidence</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"> of </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">CVT </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">during </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">2006-2016 in New York and Florida utilizing the State Inpatient Database.</span></span>
<ul>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;">CVT remains a<span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">n uncommon</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"> condition though number of admissions increased 70%.</span></span></li>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;">M<span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; text-indent: -24px; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">ean age of patients increased with number of hospitalizations in the elderly doubled.</span></span></li>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;">Incidence was highest in Blacks, followed by non-Hispanic Whites and Hispanics.</span></li>
</ul>
</li>
<li -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="Paragraph SCXW27791880 BCX0" color:="" margin:="" overflow-wrap:="" padding:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<span style="font-size:14px;">This rise in incidence may be related to increased recognition, <span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">improved diagnostic studies, </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">increased neuroimaging utilization, emerging or </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">un</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">known risk factors.</span><span class="EOP SCXW27791880 BCX0" data-ccp-props="{" style="background-color: transparent; color: windowtext; margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; line-height: 19.425px;"> </span></span></li>
</ul>
</div>
<div -webkit-tap-highlight-color:="" -webkit-user-drag:="" background-color:="" class="OutlineElement Ltr BCX0 SCXW27791880 Paragraph SCXW19586824 BCX0 OutlineElement Ltr BCX0 SCXW19586824" clear:="" color:="" cursor:="" direction:="" display:="" font-size:="" margin:="" overflow-wrap:="" overflow:="" padding:="" position:="" segoe="" style="font-family: " ui="" user-select:="" vertical-align:="">
<p class="Paragraph SCXW27791880 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; overflow-wrap: break-word; vertical-align: baseline; background-color: transparent; color: windowtext;">
<span style="font-size:14px;"><strong><span class="TextRun Underlined SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; text-decoration-line: underline; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"><span class="NormalTextRun SCXW27791880 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; background-color: inherit;">Bottom Line</span></span></strong><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"><strong>:</strong> The incidence of CVT is increasing with </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">rate of increase higher in </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">males and </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">older females</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">.</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"> </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">Consider </span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">CVT</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"> be</span><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US">yond traditional risk factors.</span><span class="EOP SCXW27791880 BCX0" data-ccp-props="{" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; line-height: 19.425px;"> </span></span></p>
</div>
</div>
<p>
</p>
<fieldset><legend>References</legend>
<ul font-size:="" segoe="" style="color: rgb(0, 0, 0); font-family: " ui="">
<li class="Paragraph SCXW27791880 BCX0" lang="EN-US" paraeid="{625207be-0715-4960-9c78-c46827f0d7fc}{177}" paraid="1444981312" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; overflow-wrap: break-word; vertical-align: baseline; background-color: transparent; color: windowtext;" xml:lang="EN-US">
<span style="font-size: 14px;"><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"><span 1px="" background-color:="" border-bottom:="" class="NormalTextRun SpellingErrorV2 SCXW27791880 BCX0" data:image="" solid="" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; background-repeat: repeat-x; background-position: left bottom; background-image: url(">Otite</span> FO, Patel S, Sharma R, <em>et al</em>. Trends in incidence and epidemiological characteristics of cerebral venous thrombosis in the United States. <em>Neurology</em>. 2020 Aug 26 [Online ahead of print]</span></span></li>
</ul>
<p class="Paragraph SCXW27791880 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; overflow-wrap: break-word; vertical-align: baseline; background-color: transparent; color: windowtext; text-align: center;">
<span style="font-size: 14px;"><span class="TextRun SCXW27791880 BCX0" data-contrast="auto" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-kerning: none; line-height: 19.425px; font-variant-ligatures: none !important;" xml:lang="EN-US"><span style="font-size: 14px;"><span class="EOP SCXW27791880 BCX0" data-ccp-props="{" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; line-height: 19.425px;"><em><strong>Follow me on Twitter @EM_NCC</strong></em></span></span></span></span></p>
</fieldset>