Title: Are anti-coagulated elderly head injured patients at risk for delayed intracranial hemorrhage?<br/>Author: Robert Flint<br/><a href='http://umem.org/profiles/faculty/2561/'>[Click to email author]</a><hr/><p class="p1" style="margin: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 14px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-color: rgb(0, 0, 0);"> <span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:16px;"><span class="s1" style="font-kerning: none;">This study looked at 69,321 head injured patients over age 65 in a health care database for delayed intracranial hemorrhage (within 90 days of visit). 58,233 patients were not on oral anticoagulants, 3081 (4.4%) were on warfarin and 8007 (11.6%) were on direct oral anticoagulants. One percent of patients not on anticoagulation and those on oral direct anticoagulation had a delayed hemorrhage while those on warfarin had a 1.8% delayed hemorrhage rate.</span></span></span></p> <p class="p2" style="margin: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 14px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-color: rgb(0, 0, 0); min-height: 17px;"> </p> <p class="p1" style="margin: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 14px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-color: rgb(0, 0, 0);"> <span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:16px;"><span class="s1" style="font-kerning: none;">Bottom Line: Direct oral anticoagulants do not increase the risk of delayed intracranial hemorrhage in patients over age 65 from baseline but warfarin does.<span class="Apple-converted-space"> </span></span></span></span></p> <fieldset><legend>References</legend>
<p class="p1" style="margin: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; line-height: normal; font-family: Helvetica; -webkit-text-stroke-color: rgb(0, 0, 0);"> <span class="s1" style="font-kerning: none;">Sharon Liu et al Delayed intracranial hemorrhage after head injury among elderly patients on anticoagulation seen in the emergency department CJEM 2022 Dec:24(8):853-861 doi:10.1007/s43678-022-00392-z.</span></p> </fieldset>