Title: Single dose aminoglycosides in complicated cystitis<br/>
Author: Robert Flint<br/>
<a href='mailto:rflint@som.umaryland.edu'>[Click to email author]</a><hr/>
Link: <a href='https://umem.org/educational_pearls/4562/'>https://umem.org/educational_pearls/4562/</a><hr/><p>The Infectious Disease Society of America in 2023 recommended a single dose of an aminoglycoside for uncomplicated cystitis treatment in those with resistance or other contraindications to first line oral agents who were otherwise well enough to be discharged. This very small study (13 participants) suggest this strategy works for complicated (“male sex, urinary flow obstruction, renal failure or transplantation, urinary retention, or indwelling catheters”) cystitis patients who could otherwise be discharged home.</p>
<fieldset><legend>References</legend><p><a href="https://onlinelibrary.wiley.com/journal/15532712"><strong>Academic Emergency Medicine</strong></a><a href="https://onlinelibrary.wiley.com/toc/15532712/2024/31/7"><strong>Volume 31, Issue 7</strong></a> p. 649-655</p>
<h2><strong>Prospective evaluation of single-dose aminoglycosides for treatment of complicated cystitis in the emergency department</strong></h2>
<p><a href="https://onlinelibrary.wiley.com/authored-by/Jenrette/Jordan+E.">Jordan E. Jenrette PharmD</a>, <a href="https://onlinelibrary.wiley.com/authored-by/Coronato/Kyle">Kyle Coronato PharmD</a>, <a href="https://onlinelibrary.wiley.com/authored-by/Miller/Matthew+A.">Matthew A. Miller PharmD</a>, <a href="https://onlinelibrary.wiley.com/authored-by/Molina/Kyle+C.">Kyle C. Molina PharmD</a>, <a href="https://onlinelibrary.wiley.com/authored-by/Quinones/Alexander">Alexander Quinones MD</a>, <a href="https://onlinelibrary.wiley.com/authored-by/Jacknin/Gabrielle">Gabrielle Jacknin PharmD</a></p>
<p>First published: 07 March 2024</p>
<p><a href="https://doi.org/10.1111/acem.14886"><strong>https://doi.org/10.1111/acem.14886</strong></a></p>
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