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<h2><strong>Title:</strong> <a href="https://umem.org/educational_pearls/4659/">Review: Spinal Cord Compression from Mets</a></h2>
<p><strong>Category:</strong> <a href="https://umem.org/educational_pearls/?category=21">Hematology/Oncology</a></p>
<p><strong>Keywords:</strong> Cord compression, cancer, metastasis, oncologic emergency <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&term=Cord+compression+cancer+metastasis+oncologic+emergency+%22last+5+years%22[dp]&db=pubmed&pubmedfilters=true" target="_blank">(PubMed Search)<i class="icon-share" title="Opens in new window"></i></a> </p>
<p>
<strong>Posted:</strong> 11/25/2024 by <a href="https://umem.org/educational_pearls/?author=655">Sarah Dubbs, MD</a>
<br/>
<a href="https://umem.org/profiles/faculty/655/">Click here to contact Sarah Dubbs, MD</a>
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<p>One of the many siginificant complications of cancers we encounter in the ED is cord compression. Here are pearls from a recently published systematic review focused on metastasis-associated spinal cord compression:</p>
<ul>
<li>Spinal cord metastatic lesions affect 5% to 10% of the oncology patients in the United States</li>
<li>Thoracic spine is most commonly involved (70%), followed by lumbosacral spine, then cervical spine </li>
<li>Primary sources of spinal metastases are the lung (31%), breast (24%), gastrointestinal tract (9%), prostate (8%), melanoma (4%), kidney (1%), lymphoma (6%), and unknown origin (2%)</li>
<li>Patients present with pain, motor/sensory deficits, and/or even autonomic dysfunction and neurogenic shock</li>
</ul>
<h3>References</h3>
<p>Vavourakis M, Sakellariou E, Galanis A, Karampinas P, Zachariou D, Tsalimas G, Marougklianis V, Argyropoulou E, Rozis M, Kaspiris A, Pneumatikos SG. Comprehensive Insights into Metastasis-Associated Spinal Cord Compression: Pathophysiology, Diagnosis, Treatment, and Prognosis: A State-of-the-Art Systematic Review. J Clin Med. 2024 Jun 19;13(12):3590. doi: 10.3390/jcm13123590. PMID: 38930119; PMCID: PMC11205147.</p>
<p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11205147/">https://pmc.ncbi.nlm.nih.gov/articles/PMC11205147/</a></p>
<h3>View this pearl on the University of Maryland, Department of Emergency Medicine's website: <a href="https://umem.org/educational_pearls/4659/">https://umem.org/educational_pearls/4659/</a></h3>
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