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<h2><strong>Title:</strong> <a href="https://umem.org/educational_pearls/4673/">Inactivity and CVD</a></h2>
<p><strong>Category:</strong> <a href="https://umem.org/educational_pearls/?category=1">Cardiology</a></p>
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<strong>Posted:</strong> 12/14/2024 by <a href="https://umem.org/educational_pearls/?author=294">Brian Corwell, MD</a>
<br/>
<a href="https://umem.org/profiles/faculty/294/">Click here to contact Brian Corwell, MD</a>
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<p>Cardiovascular disease (CVD) is the leading cause of death both in the United States and globally for both men and women.</p>
<p>Major adverse cardiovascular events (MACE) is a commonly used composite outcome.</p>
<p>MACE is defined as non-fatal stroke/acute myocardial infarction/heart failure or cardiovascular death. </p>
<p>Physical inactivity is a leading risk factor for noncommunicable diseases and death worldwide</p>
<p> Up to 5 million deaths/yr could be averted with increased physical activity</p>
<p>Regular physical activity reduces the risk of many types of cancer by 8-28%, diabetes by 17%, heart disease and CVA by 19%, and dementia by 20%.</p>
<p>Many adults and children find meeting the recommended physical activity goals very challenging.</p>
<p>A recent observational study found that just 1.5-to-4-minute small bursts of high intensity exercise throughout the day may help lower an individual’s risk of MACE.</p>
<p>To clarify, this does not mean going to the gym to do a 45-minute HIIT class</p>
<p>Vigorous intermittent lifestyle physical activity (VILPA) involves such simple things as carrying the groceries a short distance or taking the work stairs instead of the elevator.</p>
<p>Such activities are more feasible for all of us vs structured exercise for obvious reasons.</p>
<p>Study group was >100,000 middle-aged men and women. Average age 61.</p>
<p>All participants wore an activity tracker continuously for a full week.</p>
<p>This data was used to calculate VILPA bouts throughout the day.</p>
<p>Female participants with no formal exercise regimen who recorded just 3.4 minutes of VILPA a day were 50% less likely to have a MI, had a 67% decreased risk for heart failure and 45% less likely to develop any type of MACE vs those who did not clock any VILPA during their day.</p>
<p>Female participants who recorded just 1.2-1.6 minutes of VILPA a day had a 33% lower risk of MI, 40% decreased risk of heart failure and 30% lower risk of MACE.</p>
<p>In male participants, those with 5.6 minutes of VILPA each day had a 16% reduced risk of having MACE than those who did not have any VILPA. </p>
<p> Differences may be due to women’s VILPA intensity was roughly 20% greater than men </p>
<p><strong>Conclusion: Take the stairs</strong></p>
<h3>References</h3>
<p>Stamatakis E, et al. Device-measured vigorous intermittent lifestyle physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences. Br J Sports Med. 2024 Oct 28</p>
<h3>View this pearl on the University of Maryland, Department of Emergency Medicine's website: <a href="https://umem.org/educational_pearls/4673/">https://umem.org/educational_pearls/4673/</a></h3>
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