Department of Emergency Medicine

UMEM Educational Pearls

Title: ANTIDOTES: DMSA

Category: Toxicology

Keywords: DMSA, succimer, lead, arsenic, mercury (PubMed Search)

Posted: 1/7/2010 by Ellen Lemkin, MD, PharmD (Updated: 11/22/2024)
Click here to contact Ellen Lemkin, MD, PharmD

SUCCIMER (DMSA)

  • An oral agent used for the chelation of heavy metals, such as LEAD, ARSENIC and MERCURY
  • Forms a water soluble agent that chelates the heavy metal, which are renally excreted
  • Most common side effects are rashes, urticaria and GI
  • A serious adverse effect is neutropenia, which is rare

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