UMEM Educational Pearls

Title: The Nose Knows

Category: Pharmacology & Therapeutics

Keywords: Intranasal administration,fentanyl,ketorolac,sumatriptin,glucagon,desmopressin,midazolam (PubMed Search)

Posted: 10/6/2011 by Ellen Lemkin, MD, PharmD
Click here to contact Ellen Lemkin, MD, PharmD

There are an increasing number of intranasal medications commercially available for use, which is opportune as more and more intravenous medications become scarce.

These now include:

Generic name	Brand Name	Usage
Fentanyl	Instanyl	Opiate analgesic
Ketorolac	Sprix	NSAID analgesic
Desmopressin (DDAVP)	Stimate	Bleeding
Vitamin B12	Nasobal	Anti-migraine (yes!)
Sumatriptan	Imitrex	Anti-migraine
Zolmitripran	Zomig	Anti-migraine

*******In addition, you can administer glucagon, midazolam and narcan intranasally as well.

References

Veldhorst-Jassen, NM, Fiddelers AA, Paul-Hugo M et all. A review of the clinical pharmacokinetics of opioids, benzodiazepines, and antimigraine drugs delivered intranasally. Clinical Therapeutics Nov 12, 20009;31(12):2954-87.

Wolfe TR, Braude DA. Intranasal Medication Delivery for Children: A Brief Review and Update. Pediatrics 2010;126;532:532-7.