Adenosine should be used with great caution in patients with wide complex tachycardia for two major reasons: 1. Adenosine should never be used as diagnostic maneuver to decide whether someone has ventricular tachycardia vs. SVT. Adenosine is well-reported to convert certain types of VT. 2. If the WCT is irregular, this may be atrial fibrillation with WPW, in which case adenosine is well-known to produce ventricular fibrillation.
