UMEM Educational Pearls

Category: Vascular

Title: More Fenoldopam Pearls

Keywords: Fenoldopam, Hypertension (PubMed Search)

Posted: 1/28/2008 by Rob Rogers, MD (Updated: 2/18/2020)
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Fenoldopam Pearls

Intravenous Fenoldopam has been shown in recent years to be a very effective antihypertensive medication. Studies have compared it to Nitroprusside (Nipride), the older generation "gold standard" antihypertensive, and have found to be just as effective.

  • Think of Fenoldopam as Nipride without the toxicity....taste great, less filling
  • Works by peripheral dopamine agonism
  • Increases renal blood flow and induces a natriuresis (patient pees sodium)-so works well in our chronic kidney disease and ESRD patients
  • Easy to titrate and very well tolerated
  • Contraindication in patients with glaucoma-The drug elevates IOP.

Journal of Hypertension 2007