Keywords: ketamine, agitation, prehospital, haloperidol (PubMed Search)
Ketamine is gaining traction as a prehospital option for managing severe agitation or excited delirium syndrome. Previous reports have mostly been case series, but a new prospective study adds some important information that may help delineate ketamine's role in this setting.  The study and an accompanying commentary are both open access. 
What They Did
Open-label before-and-after prospective comparison of haloperidol (10 mg IM) versus ketamine (5 mg/kg IM) for the treatment of acute undifferentiated agitation.
What They Found
Appliation to Clinical Practice
Follow me on Twitter (@PharmERToxGuy)