Keywords: BP, Hypertension, Angioedema (PubMed Search)
Direct Renin Inhibitor-Aliskiren (Tekturna)
This drug is the 1st in a new class of antihypertensives called direct renin inhibitors-1st approved in 2007. This drug, along with three others being developed, inhibits the entire Renin-Angiotensin-Aldosterone System (RAAS) which has been shown to lead to definitive 24 hour blood pressure control.
Why should emergency physicians care, you ask?
J Hypertension March 2007