Keywords: naloxone, pulmonary edema, aspiration, overdose (PubMed Search)
Pulmonary complications - aspiration, pulmonary edema, etc. are frequently reported in both heroin intoxication and in reversal of opioid overdose with naloxone.
Suspected opioid overdose victims (N=1831) who received naloxone from EMS providers were studied retrospectively. Pulmonary complications were defined as pulmonary edema, aspiration pneumonia and aspiration pneumonitis.
Higher out of hospital naloxone administration is associated with increased odds of developing pulmonary complications