Somatostatin-analog that supresses insulin secretion but also treats acromegaly, esophageal varices and secretory diarrhea
Sulfonylurea-induced hypoglycemia requires frequent monitoring and administration of intravenous dextrose
Octreotide is considered antidotal therapy since it turns off insulin secretion that is caused by sulfonylureas
Recent article by Fasano et al Ann Emerg Med 2008 showed that octreotide 75 mcg SQ one-time in the ED was superior to "traditional" therapy with fewer recurrent hypoglycemic episodes during the patient's hospitalization.
Excellent article worth reading, even if its just the abstract
