UMEM Educational Pearls - By Robert Flint

Title: 2025 HTN guidelines

Category: Cardiology

Keywords: Hypertension, treatment, (PubMed Search)

Posted: 9/6/2025 by Robert Flint, MD (Updated: 2/1/2026)
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From this position statement on management of HTN key points are beta blockers are a second line medication choice, dual therapy in a combination pill is often warranted and primary medications should be thiazides, long acting calcium channel blockers, ACE or Arbs. 

 

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Title: More data on intensive blood pressure control in post-thrombolysis CVA patients

Category: Neurology

Keywords: CVA, blood pressure management, aggressive, edema (PubMed Search)

Posted: 8/25/2025 by Robert Flint, MD (Updated: 8/30/2025)
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While this study is imperfect and may not be measuring patient important outcomes, it does fit with other literature on the topic of intensive blood pressure control in patients with acute ischemic stroke. These patients were randomized to aggressive blood pressure control  (SBP 130-140 within 1 hour of TPA administration continued for 72 hours) or the standard SBP <180. Repeat imaging was performed to assess the degree of cerebral swelling that each group developed. There was no difference in swelling between the two groups. 

Take away is aggressive blood pressure management in this group of ischemic stroke patients does not seem to be beneficial.

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Title: Frailty as troponin: an analogy

Category: Geriatrics

Keywords: frailty, geriatrics, troponin, syndrome (PubMed Search)

Posted: 8/25/2025 by Robert Flint, MD (Updated: 8/27/2025)
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This editorial reminds us about the use of frailty measures in the geriatric population. 

The authors write that frailty “describes a state of vulnerability causing an impaired ability to maintain homeostasis due to reduced physiologic reserve. Frailty is associated with disability, multimorbidity, cognitive impairment, institutionalization, and mortality. **Analogous to troponin testing, frailty assessment has been used to risk stratify older adults.**”

They also remind us that frailty is a syndrome not a disease in and of itself. It impacts how disease affects the patient and should inform our care, but not generate ageism or therapeutic nihilism. 

Once frailty is identified, it allows for further assessment looking at the “Geriatric 5M's framework: Mind, Mobility, Medications, Multicomplexity, and Matters Most.”

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Title: Head CT in older patients on antithrombotics: are we over doing it?

Category: Trauma

Keywords: head injury, geriatric, antithrombotic, CT imaging (PubMed Search)

Posted: 8/25/2025 by Robert Flint, MD (Updated: 2/1/2026)
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In this retrospective study at 103 hospitals of patients over age 65 who received a head CT:

5948 total patients

3177 (53%) were on at least one anti-thrombotic (warfarin, direct oral anticoag, or anti-platelet agent)

781 (13%) had inter cranial hemorrhage. (ICH)

No form of AC showed an increased risk of ICH. 

Risk factors for ICH were: “a high-level fall, a Glasgow coma scale of 14, a cutaneous head impact , vomiting, amnesia, a suspected skull vault fracture or of facial bones fracture”

To me this really begs the question are we ordering head CTs on the right patients?  Was there any indication of head injury in these patients or did the mere presence of a patient on AC prompt the imaging order? More work should be done to prevent needless imaging cost, patient time in the emergency department and radiologist work load/turn around time.

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Title: Hemothorax, chest tubes, and volume calculation

Category: Trauma

Keywords: chest tube, tube thoracostomy, hemothorax, volume (PubMed Search)

Posted: 8/23/2025 by Robert Flint, MD (Updated: 8/24/2025)
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Question

Over 300 ml of blood on a chest CT in a traumatically injured patient requires a tube thoracostomy.  How do you calculate 300 ml of blood on a chest CT?

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Title: Pneumothorax reminders

Category: Trauma

Keywords: Pneumothorax, cheat tube, indication (PubMed Search)

Posted: 8/17/2025 by Robert Flint, MD (Updated: 2/1/2026)
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This review article answers the basic question: when does a traumatic pneumothorax require tube thoracostomy? 

“A pneumothorax greater than 20% of the thoracic volume on chest x-ray or greater than 35 mm on CT, measured radially from the chest wall to the lung parenchyma, should be treated with tube thoracostomy. Pneumothoraces smaller than this may be observed; approximately 10% of these will fail observation and require tube thoracostomy treatment.”

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Title: Post-gunshot health sequela

Category: Trauma

Keywords: Gunshot, ptsd, reinjury (PubMed Search)

Posted: 8/10/2025 by Robert Flint, MD (Updated: 2/1/2026)
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This paper outlines the long term effects of surviving a gunshot wound. The authors conclude:

“Firearm injury survivors frequently experience chronic pain, nerve injury, retained bullet fragments that may cause lead toxicity, physical limitations, and PTSD and are at risk for reinjury. In addition to supportive medical and psychiatric care, survivors of firearm injury may benefit from health care–based violence intervention programs.”

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Title: Prehospital hypothermia and trauma mortality

Category: Trauma

Keywords: Hypothermia, trauma, mortality (PubMed Search)

Posted: 8/3/2025 by Robert Flint, MD (Updated: 2/1/2026)
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Looking at a trauma database of over 3 million patients, 1% presented with prehospital hypothermia (<35 degrees C). These patients had longer hospital stays, higher resource utilization and higher mortality.  Even isolated head injury patients with hypothermia had worse outcomes. Rewarming did increase survival slightly for all patients. 
Take away: rewarm hypothermic trauma patients as soon as possible to improve mortality.

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Title: Factors associated with anxiety in older patients

Category: Geriatrics

Keywords: Anxiety, older, risk (PubMed Search)

Posted: 8/2/2025 by Robert Flint, MD (Updated: 2/1/2026)
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A scoping review of the literature regarding anxiety in older patients found the follow areas had the biggest impact on anxiety level:

“The variables most strongly associated with anxiety—either as risk or protective factors—are age, female gender, physical activity, physical health conditions, depression, perceived and family support, and social participation. New variables linked to anxiety include body mass index (BMI) and dietary habits.”

Asking questions related to these areas can give you a better picture of your patient’s risk for anxiety.

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Title: Antibiotics for abdominal gunshot wounds associated with fractures

Category: Trauma

Keywords: Gun shot, antibiotics, prophylaxis, fracture (PubMed Search)

Posted: 7/31/2025 by Robert Flint, MD (Updated: 2/1/2026)
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Looking at 140 patients retrospectively who had abdominal gunshot wounds with associated fractures, prophylactic antibiotics longer than three days did not offer any benefit in preventing fracture infection. Only two patients experienced fracture related infections and 65 total experienced any infection related complications. 
From and ED standpoint, it appears reasonable to give a dose of antibiotics in this very rare subset of gunshot wound patients.

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Title: Geriatric trauma triage failure

Category: Geriatrics

Keywords: Geriatric l, trauma, triage (PubMed Search)

Posted: 7/30/2025 by Robert Flint, MD (Updated: 2/1/2026)
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This prospective cohort study from Germany found an under triage rate of 58% of trauma patients over 70 years presenting to 12 trauma centers. One area that consistently lead to undertriage was not using a systolic blood pressure under 110 as a criteria for trauma team activation. 
The older cohort had 3 times the mortality than younger, were more likely not to arrive by helicopter and mechanism was more commonly ground level fall. This study echos many others in USA and Australia. Better trauma triage criteria are needed for older patients.

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A retrospective, single Australian center review of 300 patients who had blunt cerebral vascular injuries found:

-9.8% had an inpatient CVA

-Most occurred in first 72 hours

-Those receiving no anti coagulation or antiplatelets had 28% CVA incidence. 
-Those treated had a 3.6% CVA incidence (anti platelets were better than anti coagulation)

-Carotid artery injury was less common than vertebral artery but had higher frequency of CVA

-associated factors: low GCS, rib fractures, severe trauma 

Take away: non-treatment of blunt cerebral vascular injuries had higher inpatient stroke risk. Antiplatelet agents such as aspirin and Clopidogrel performed better than anticoagulants

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Title: Missed injuries in trauma patients

Category: Trauma

Keywords: Mussed injuries, trauma, tertiary survey, (PubMed Search)

Posted: 7/27/2025 by Robert Flint, MD
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This paper looked at the literature regarding missed injuries in trauma patients. Missed injuries was defined as an injury discovered after the patient was discharged. Most of the missed injuries and causes are not novel but are worthy of remembering. 

They suggest a Trauma Tertiary Survey helps prevent missed injury. “Tertiary Survey (TTS), which includes a thorough in-hospital re-examination and a review of diagnostic investigations within the first 24 h, has been shown to significantly reduce the occurrence of missed injuries (1–9 %) in severe trauma patients found after a primary and secondary survey.”  This concept is similar to a discharge time out in emergency medicine where all data is reviewed, viral signals are confirmed normal and a team discharge is performed. 
The paper offers these suggestions to avoid missed injuries:

1.

Standardize Tertiary Trauma Surveys (TTS).

2.

Be Cognizant of Cognitive Biases (e.g., Anchoring Bias).

3.

Repeat Imaging When Clinically Indicated.

4.

Use Protocolized Imaging Techniques (CT/MRI).

5.

Ensure Radiology-Trauma Communication.

6.

Prioritize High-Risk Populations.

7.

Implement Peer Review or Double-Check Systems.

8.

Encourage a Culture of Collaboration and Humility.

9.

Limit Provider Fatigue and Overload.

10.

Create Tailored Checklists for Subtle Injuries.

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Title: Traumatic Brain Injury Management Reminders

Category: Trauma

Keywords: TBI, management, parameters (PubMed Search)

Posted: 7/20/2025 by Robert Flint, MD (Updated: 2/1/2026)
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Outcomes in traumatic brain injury are improved when physiologic homeostasis is achieved as soon as possible after injury. Here are the American College of Surgeons’ recommendations. Note SBP over 110 and a hemoglobin over 7. A study looking at a more liberal transfusion target showed worse ARDS and no mortality benefit. 

 

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Title: Higher MAP for critically ill older patients: is this the answer

Category: Geriatrics

Keywords: Geriatric, critical care, vasopressors. (PubMed Search)

Posted: 7/12/2025 by Robert Flint, MD (Updated: 7/14/2025)
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An open label pragmatic study in 29 Japanese hospitals randomized septic shock patients over age 65 to either a high (MAP 80-85) or control (65-70) group. They then looked at all cause 90 day mortality. The study was stopped early due to a significantly higher percentage of mortality in the higher MAP group. 
The study isn’t blinded and is only done in one country, however it does raise the question of what is the ideal MAP for older septic shock patients.

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Title: Effect of vehicle size on pedestrian and cyclist fatalities

Category: Trauma

Keywords: Pedestrian, fatality, injury, cyclist (PubMed Search)

Posted: 7/12/2025 by Robert Flint, MD (Updated: 2/1/2026)
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This study from Great Britain compared fatalities for pedestrians and cyclist struck by motor vehicles based on vehicle body type. They found :

“We conclude that in Great Britain, being hit by an SUV as opposed to a passenger car increases injury severity among pedestrians and cyclists, with the strongest effect in children.“

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Title: Age friendly hospital quality measure

Category: Geriatrics

Keywords: Age friendly, geriatric, healthcare, quality improvement (PubMed Search)

Posted: 7/6/2025 by Robert Flint, MD (Updated: 2/1/2026)
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In mid-2024 the Center for Medicare and Medicaid Services introduced a new quality measure entitled Age Friendly Hospital Measure. The initial phase went into effect 1/1/25. It is built around programs from the American College of Surgeons, the American College of Emergency Physicians as well as the Institute for Healthcare Improvement (IHI). It is modeled around the IHI’s 4M Framework. 

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Title: Use of shock index in compensated shock state to predict transfusion

Category: Trauma

Keywords: Shock index, transfusion, hypotension (PubMed Search)

Posted: 7/5/2025 by Robert Flint, MD (Updated: 2/1/2026)
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These authors looked at 5958 trauma patients arriving at their trauma center with a systolic blood pressure greater than 90. They calculated shock index (heart rate /sbp) for all of these and then looked at who received a blood transfusion within one hour of arrival.  211 patients received blood in that time frame.  “Patients were stratified by SI using the following thresholds: ? 0.7, > 0.7 to 0.9, > 0.9 to 1.1, > 1.1 to 1.3, and > 1.3.”
“A main effect was observed for shock index with increased risk for required transfusion for patients with admission shock index >0.7 (P < 0.001). In comparison to shock index of ? 0.7, odds ratios were 2.5(1.7 - 3.8), 8.2(5.4 - 12.2), 24.9(15.1 - 41.1), 59.0(32.0 - 108.6) for each categorical increase in SI.”

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Title: Facial Fracture Transfer Guidelines

Category: Trauma

Keywords: facial fracture, transfer, guidelines (PubMed Search)

Posted: 6/29/2025 by Robert Flint, MD (Updated: 7/2/2025)
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Based on a review of  511 patients transferred to a level one trauma center for evaluation of facial fractures, this group developed the Facial Fracture Transfer Guidelines.  they found that over half of the patients transferred to them did not require intervention and were discharged within 6 hours. These guidelines are meant to decrease unneeded transfers yet provide appropriate care to those with traumatic facial injuries. 

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Title: Facial Fracture Review

Category: Trauma

Keywords: facial fracture, Le Fort, orbital fracture (PubMed Search)

Posted: 6/29/2025 by Robert Flint, MD (Updated: 2/1/2026)
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Most common facial fracture is the nasal fracture followed by the zygomatic arch fractures. 

Le Fort Classification of facial fractures/facial stability. The higher the number, the more unstable. 

Orbital blow out fractures may entrap the ocular muscles leading to eye immobility in various directions. 

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