Category: Cardiology
Keywords: syncope, pre-syncope (PubMed Search)
Posted: 6/27/2024 by Robert Flint, MD
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The systematic review of presyncope literature found that presyncope should be treated the same as syncope in terms of work up and disposition.
“In conclusion, the prevalence of short-term serious outcomes among ED patients with presyncope ranges from one in four to one in 20, with arrhythmia being the most common serious outcome. Our review indicates that presyncope may carry a similar risk to syncope, and hence, the same level of caution should be exercised for ED presyncope management as that of ED syncope.”
Serious outcomes among emergency department patients with presyncope: A systematic review
Hadi Mirfazaelian MD, MSc, Ian Stiell MD, MSc, FRCPC, Rasoul Masoomi PhD, Khazar Garjani MD, Venkatesh Thiruganasambandamoorthy MBBS, CCFP-EM, MSc
First published: 09 June 2024 Academic Emergency Medicine
Category: Pharmacology & Therapeutics
Keywords: alcohol use disorder, phenobarbital, naloxone, treatment (PubMed Search)
Posted: 6/23/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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Two recommendations from the recent GRACE 4 publication in Academic Emergency Medicine to consider:
1. Use phenobarbital along with benzodiazepines in patients with moderate to severe alcohol withdrawal. The evidence isn’t robust but is positive when compared to benzos alone.
2. Adults with alcohol use disorder can benefit from anti-craving medications such as naloxone and gabapentin at time of discharge.
Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department Bjug Borgundvaag PhD, MD, CCFP(EM), Fernanda Bellolio MD, MSc, Isabelle Miles MD, Evan S. Schwarz MD, Sameer Sharif MD, MSc, Mark K. Su MD, MPH, Kevin Baumgartner MD, David B. Liss MD, Hasan Sheikh MD, MPA, Jody Vogel MD, MSc, MSW, Emily B. Austin MD, Suneel Upadhye MD, MSc, Michelle Klaiman MD, FRCPC, DABAM, Robert Vellend, Anna Munkley, Christopher R. Carpenter MD, MSc
First published: 15 May 2024
Academic Emergency Medicine https://doi.org/10.1111/acem.14911
Category: Trauma
Keywords: troponin fall geriatric trauma (PubMed Search)
Posted: 6/20/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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A prospective European study of patients over age 65 presenting with a ground level fall obtained troponin levels to ascertain if myocardial infarction was a cause of the ground level fall. Troponin levels were elevated in a majority of patients however only 0.5% were defined as having a myocardial infarction. Of the 3% who died within 1 year, troponin was found to be higher than those that survived the one-year study period. The authors concluded “Our data do not support the opinion that falls may be a common presenting feature of MI. We discourage routine troponin testing in this population. However, hs-cTnT and hs-cTnI were both found to have prognostic properties for mortality prediction up to 1?year.”
Diagnostic and prognostic value of cardiac troponins in emergency department patients presenting after a fall: A prospective, multicenter study
Tanguy Espejo, Lukas Terhalle, Alexandra Malinovska MD, Henk B. Riedel MD, Laura Arntz MD, Livia Hafner, Karen Delport-Lehnen MD, Joanna Zuppinger MD,
First published: 26 March 2024
Academic Emergency Medicine
Category: Trauma
Keywords: hemorrhage, tourniquet, innovation, Delphi (PubMed Search)
Posted: 6/9/2024 by Robert Flint, MD
(Updated: 6/16/2024)
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Appropriately, a great deal of time and energy is being expended to educate on the use of tourniquets to prevent mass hemorrhage. Are the current generation of tourniquets the best that we can have? These authors performed a Delphi study to assess needs with tourniquet design.
They concluded the next generation of tourniquets should have the following: “Capable of being used longer than 2 hours, applied and monitored by anyone, data displays, semiautomated capabilities with inherent overrides, automated monitoring with notifications and alerts, and provide recommended actions.”
Veazey, Sena R. MS; Mike, Jared F. PhD; Hull, Darke R. BS; Ryan, Kathy L. PhD; Salinas, Jose PhD; Kragh, John F. Jr MD. Next-generation tourniquet: Recommendations for future capabilities and design requirements. Journal of Trauma and Acute Care Surgery 96(6):p 949-954, June 2024. | DOI: 10.1097/TA.0000000000004237
Category: Trauma
Keywords: BIG, transfer, head trauma, brain injury (PubMed Search)
Posted: 6/9/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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This study used the modified Brain injury Guidelines retrospectively to assess whether the guidelines would have saved transfers to their level one facility safely. They concluded the guidelines would have effectively prevented unnecessary mBIG 1 and mBIG2 transfers with no patient harm.
TABLE 1 - Modified Brain Injury Guidelines Radiologic Stratification, as per Kahn et al.
mBIG 1 | mBIG 2 | mBIG 3 | |
---|---|---|---|
Skull fracture | No | Non-displaced | Displaced |
SDH | ?4 mm | 4–7.9 mm | ?8 mm |
EDH | No | No | Yes |
SAH | ?3 sulci and <1 mm | Single hemisphere or 1–3 mm | Bihemisphere or >3 mm |
IVH | No | No | Yes |
IPH | ?4 mm | 4–7.9 mm | ?8 mm or multiple |
EDH, epidural hematoma; IPH, intraparenchymal hemorrhage; IVH, intraventricular hemorrhage; SAH, subarachnoid hemorrhage.
Shen, Aricia MD; Mizraki, Nathaniel MD; Maya, Marcel MD; Torbati, Sam MD; Lahiri, Shouri MD; Chu, Ray MD; Margulies, Daniel R. MD; Barmparas, Galinos MD. Reducing low-value interhospital transfers for mild traumatic brain injury. Journal of Trauma and Acute Care Surgery 96(6):p 944-948, June 2024. | DOI: 10.1097/TA.0000000000004291
Category: Trauma
Posted: 5/29/2024 by Robert Flint, MD
(Updated: 6/1/2024)
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In this Scandinavian study looking at 2,362 head injury patients on oral anticoagulants, the authors found only 5 cases of delayed hemorrhage and none of the five underwent neurosurgery. The authors concluded:
“In patients with head trauma, on oral anticoagulation, the incidence of clinically relevant delayed intracranial hemorrhage was found to be less than one in a thousand, with detection occurring four days or later after initial presentation.”
It would appear based on this study and others that it is safe to discharge these patients with a normal head CT and giving strict return precautions for headache, nausea, vomiting or other changes.
André, L., Björkelund, A., Ekelund, U. et al. The prevalence of clinically relevant delayed intracranial hemorrhage in head trauma patients treated with oral anticoagulants is very low: a retrospective cohort register study. Scand J Trauma Resusc Emerg Med 32, 42 (2024). https://doi.org/10.1186/s13049-024-01214-0
Category: Geriatrics
Keywords: Geriatrics, frailty, screening (PubMed Search)
Posted: 5/27/2024 by Robert Flint, MD
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This Delphi study and companion editorial highlight current thought on frailty screen in emergency department patients. Key takeaways are:
Emergency departments should be instituting procedures that incorporate screening older patients for frailty. These references are a good starting point.
Category: Trauma
Keywords: Lefort, facial, trauma, fracture (PubMed Search)
Posted: 5/26/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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On exam, assess for facial instability and airway patency. CT scan is the imaging of choice. The higher the number, the more complex the fracture, the more unstable and the more difficult the airway managment will be. Look for open lacerations or blood in the sinuses and treat with antibiotics if these are found. Consult ENT or plastics urgently for further management.
The reference is a nice review of these fractures
Category: Cardiology
Posted: 5/24/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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Category: Ultrasound
Keywords: Abdomen, ultrasound, trauma, contrast (PubMed Search)
Posted: 5/23/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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This very small study looked at the utility of using IV contrast media to enhance abdominal sonography in identifying injuries in blunt abdominal trauma patients. The comparison was CT scanning of the abdomen to identify injuries. The study concluded:
“With the addition of contrast and careful inspection of solid organs, abdominal sonography with contrast performed by the emergency physician improves the ability to rule out traumatic findings on abdominal CT. CEUS performed by emergency physicians may miss injuries, especially in the absence of free fluid, in cases of low-grade injuries, simultaneous injuries, or poor-quality examinations.”
To me, this is a limited study and the technique is not ready for wide spread use but further study is warranted.
Viviane Donner MD, Julian Thaler MD, Wolf E Hautz Prof. Dr.Med, MME, Thomas Christian Sauter Prof. Dr.Med, MME, Daniel Ott MD, Karsten Klingberg MD, Aristomenis K Exadaktylos Prof.Dr.Med, Beat Lehmann MD
First published: 19 April 2024
Journal of the American College of Emergency Physicians OpenVolume 5, Issue 2
Category: Trauma
Keywords: vasopressor, hemorrhage, shock, trauma (PubMed Search)
Posted: 5/19/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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In this podcast, the concept of vasopressor use in hemorrhagic shock is discussed. Key take away points:
Category: Administration
Posted: 5/13/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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This retrospective study looked at patients diagnosed with urinary tract infections receiving an IV dose of antibiotics prior to discharge and compared ED length of stay and return visit rate. They found:
“Parenteral antibiotic administration in the ED was associated with a 60-minute increase in ED LOS compared with those who received an oral antibiotic (P < 0.001) and a 30-minute increase in ED LOS compared with no antibiotic (P < 0.001). No differences were observed in revisits to the ED at 72 hours”
Appears no benefit to the practice of IV antibiotics prior to discharge in UTI patients.
Mohammed A. Alrashed Stephen J. Perona Mark C. Borgstrom Elias Ramirez-Moreno
JAPhA VOLUME 64, ISSUE 3, 102020, MAY 2024
Published:January 29, 2024DOI:https://doi.org/10.1016/j.japh.2024.01.016
Category: Trauma
Posted: 5/12/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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Hemodynamic instability in trauma patients is most often associated with hemorrhagic shock, however, there is an entity known as brain injury associated shock (BIAS). BIAS is thought to be associated with catecholamine surges secondary to brain injury. BIAS is found in both isolated head injury pts as well as multi-trauma patients. Studies have identified BIAS in 13% of adult trauma patients and up to 40% of pediatric major trauma patients.
We know hypotension in brain injury worsens outcome. We should assume hemorrhagic etiology until we prove otherwise. Once we suspect BIAS and have excluded hemorrhagic etiology our strategy should switch to blood pressure support using non-blood product management.
Partyka C, Alexiou A, Williams J, Bliss J, Miller M, Ferguson I. Brain Injury Associated Shock: An Under-Recognized and Challenging Prehospital Phenomenon. Prehospital and Disaster Medicine. Published online 2024:1-6. doi:10.1017/S1049023X24000359
Category: Trauma
Keywords: trauma, blunt, cardiac injury, shock, thoracic (PubMed Search)
Posted: 5/5/2024 by Robert Flint, MD
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Blunt Cardiac Injury is a continuum from asymptomatic, not clinically relevant to catastrophic, life ending disease . Consider blunt cardiac injury in patients with significant force to the chest wall or sudden deceleration injuries (motor vehicle crashes, motorcycle crashes, falls from height etc.). This algorithm is helpful when working up patients suspected of having significant blunt cardiac injury.
Biffl, Walter L. MD; Fawley, Jason A. MD; Mohan, Rajeev C. MD. Diagnosis and management of blunt cardiac injury: What you need to know. Journal of Trauma and Acute Care Surgery 96(5):p 685-693, May 2024. | DOI: 10.1097/TA.0000000000004216
Category: Cardiology
Posted: 4/28/2024 by Robert Flint, MD
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In a cohort of 93,512 ED patients discharged with a diagnosis of hypertension there were 4400 who received a prescription for antihypertensives. The group receiving a prescription had fewer 30 day revisits and adverse events such as MI, CHF, etc.
Previous study’s have found it is safe to prescribe antihypertensives from the ED.
This study is limited by the fact it is not a randomized control trial and there are many variables as to why the select patients received prescriptions
The authors conclude: “Prescription antihypertensive therapy for discharged ED patients is associated with a 30-day decrease in severe adverse events and ED revisit rate.”
Brett R. Todd MD, Yuying Xing PhD, Lili Zhao PhD, An Nguyen MD, Robert Swor DO, Lauren Eberhardt, Amit Bahl MD
Journal of the American College of Emergency Physicians OpenVolume 5, Issue 2 e13138
Category: Trauma
Posted: 4/24/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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A small study retrospectively looking at recorded calls to a level 1 trauma center transfer line specifically looking at patients who died or were discharged to hospice without surgical intervention found only 10% had goals of care discussed prior to transfer. Most were brain hemorrhage patients.
As a transferring facility, clearly outlining goals of care and addressing futility of care can have a major impact on trauma transfers and the cost and family burden associated with transfers.
Trenga-Schein, Nellie BA; Zonies, David MD, MPH, MBA, FACS, FCCM, FACHE; Cook, Mackenzie MD, FACS
Journal of Trauma and Acute Care Surgery 96(4):p 583-588, April 2024. | DOI: 10.1097/TA.0000000000004215
Category: Trauma
Posted: 4/21/2024 by Robert Flint, MD
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PECARN has a decision tool to identify blunt trauma patients under age 18 who are low probability for important intra-abdominal injuries. The questions to ask are:
Answering no to all yields <0.1% chance of intra-abdominal trauma requiring intervention. (See MedCalc link for other calculations)
A prospective validation study in the Lancet yielded 100% sensitivity and negative predictive value in 7542 patients under age 18
This tool can likely be used to guide imaging choices in pediatric blunt abdominal trauma patients
Category: Trauma
Posted: 4/14/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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This study looked at survival pre and post implementation of an airway guideline for prehospital traumatic brain injury (TBI) patients who received positive pressure airway interventions. The guideline “focused on the avoidance and aggressive treatment of hypotension and 3 airway-related goals: (1) prevention or treatment of hypoxia through early, high-flow oxygen administration; (2) airway interventions to optimize oxygenation or ventilation when high-flow oxygen was insufficient; and (3) prevention of hyperventilation or hypocapnia by using ventilation adjuncts (ie, rate timers, flow-controlled ventilation bags, end-tidal carbon dioxide monitoring).”
Post implementation, survival to admission increased in all severity levels of TBI and in the most severely injured, survival to discharge improved.
Useful for those involved in prehospital education and as a reminder for in hospital airway management in TBI patients.
Gaither JB, Spaite DW, Bobrow BJ, et al. EMS Treatment Guidelines in Major Traumatic Brain Injury With Positive Pressure Ventilation. JAMA Surg. 2024;159(4):363–372. doi:10.1001/jamasurg.2023.7155
Category: Trauma
Keywords: Trauma, blood pressure, shock index, predictor, mortality (PubMed Search)
Posted: 4/8/2024 by Robert Flint, MD
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Traditionally, a systolic blood pressure (SBP) of 90 has been used as a marker of severe illness in trauma patients. This study looked at a large database and found shock index (SI) and systolic blood pressure were the best predictors of early mortality in trauma patients.
They found:
prehospital SI 0.9 and SBP 110,
ED SI 0.9 and SBP 112,
and
in elderly
prehospital SI 0.8 SBP 116
ED SI 0.8 SBP 121
were the cutoffs to predict early mortality.
We should rethink our protocols and approach to trauma patients using a higher systolic blood pressure than 90. Also note elderly had a different number than younger trauma patients.
April MD, Fisher AD, Rizzo JA, Wright FL, Winkle JM, Schauer SG. Early Vital Sign Thresholds Associated with 24-Hour Mortality among Trauma Patients: A Trauma Quality Improvement Program (TQIP) Study. Prehosp Disaster Med. 2024 Apr 2:1-5. doi: 10.1017/S1049023X24000207. Epub ahead of print. PMID: 38563282.
Category: Trauma
Keywords: Marker, penetrating trauma, radiopaque (PubMed Search)
Posted: 4/7/2024 by Robert Flint, MD
(Updated: 11/26/2024)
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Using radiopaque markers such as paperclips to mark penetrating wounds prior to radiographs has been taught in trauma bays for decades. This article points out there is no evidence to support this practice and is purely based on expert opinion. With the heavy use of CT imaging to assess wound tracks, the use of markers on plain films appears to be of limited utility.
Sarfaraz K, Nemeth J, Bahreini M. The use of radiopaque markers is medical dogma. Acad Emerg Med. 2024 Feb;31(2):193-194. doi: 10.1111/acem.14858. Epub 2024 Feb 6. PMID: 38112251.