UMEM Educational Pearls

Category: Toxicology

Title: Drugs That Develop Lupus Anticoagulants

Keywords: lupus, anticoagulants, thrombosis (PubMed Search)

Posted: 5/19/2011 by Fermin Barrueto, MD (Updated: 12/14/2019)
Click here to contact Fermin Barrueto, MD

The following list of medications have been associated with the development of Lupus Anticoagulants. Though it sounds like they should anticoagulate, they interfere with the Protein C system which means that they could induce a pro-thrombotic state - good short list to know:

Chlorpromazine (Thorazine

Procainamide (sorry Amal, I know you love that drug)

Hydralazine

Quinidine

Phenytoin