UMEM Educational Pearls

Category: Neurology

Title: Transient Global Amnesia

Keywords: amnesia, TIA, memory (PubMed Search)

Posted: 9/5/2007 by Aisha Liferidge, MD (Updated: 10/19/2019)
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Transient Global Amnesia (TGA) is a rare (5 to 11 cases per 100,000 persons per year), but clinically well-defined disorder defined as an acute episode of short-term memory loss, in the absence of any neurologic signs or symptoms, which resolves within 24 hours. TGA is typically triggered by an event such as valsalva, exercise, emotional stress, sexual intercourse, immersion in cold water, painful stimuli, and severe exertion. While there are widely used diagnostic criteria, TGA is primarily a clinical diagnosis and one of exclusion. While TGA is benign, self-limiting, and there is no specific treatment other than reassurance, it is important to recognize and differentiate TGA from TIA, which has different prognostic implications. Agrawal, et al. "Transient Global Amnesia: An Uncommon Differential Diagnosis of Transient Ischemic Attack." Hospital Physician 43:8.