vasculitis of small vessels with neutrophilic infiltration of venules and arterioles
classic triad: painful recurrent oral and genital ulcers with inflammatory eye disease
key finding of recurrent buccalapthous ulcers (nearly 100% of patients)
diagnosis is made when recurrence of oral ulceration occurs at least 3 times in 1 year plus 2 of the following: recurrent genital ulceration , eye lesions, skin lesions, or positive pathergy test.
initial ED treatment is corticosteroids (oral or topical). Reserve colchicine and pentoxifylline for ulcerative maifestations.
