UMEM Educational Pearls

Category: Toxicology

Title: Carbamazepine

Keywords: anticonvulsant, carbamazepine, seizure (PubMed Search)

Posted: 11/2/2007 by Fermin Barrueto, MD (Updated: 7/10/2020)
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Carbamazepine

  • Anticonvulsant that can be monitored (you can draw a level)
  • Toxicity resembles a TCA with seizures and cardiac conduction delays
  • > 40 mcg/mL assoc with coma, seizures, respiratory failure and cardiac toxicity
  • Treat widened QRS comples with sodium bicarbonate
  • Adsorbs very well to activated charcoal, multi-dose may be required