UMEM Educational Pearls

Category: Critical Care

Title: Pulmonary Hypertension Pearls

Keywords: pulmonary hypertension, hypotension, calcium channel blockers (PubMed Search)

Posted: 1/8/2008 by Mike Winters, MD (Updated: 10/20/2020)
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Pulmonary Hypertension Pearls

We are beginning to see more and more patients with pulmonary hypertension (PAH),  many of whom are on continuous IV infusions of new medications.  With that in mind, here are a few pearls:

  • The most common causes of rapid deterioration in patients with PAH are: catheter occlusion/pump malfunction, pneumonia, indwelling catheter infection, RV ischemia, PE, and GI bleeding
  • Hypotension is usually due to worsening RV failure and less likely to hypovolemia
  • If a catheter occlusion or pump failure is found, the drug should be restarted as soon as possible through an alternative access (including peripheral)
  • Calcium channel blockers, a prior treatment for PAH, are no longer indicated and should not be given