UMEM Educational Pearls

Category: Critical Care

Title: Acute Kidney Injury (AKI)

Keywords: aki, renal failure, acute kidney injury (PubMed Search)

Posted: 2/2/2016 by Feras Khan, MD
Click here to contact Feras Khan, MD

  • AKI can be seen in up to 40% of ICU patients
  • Around 5-10% require treatment with renal replacement therapies
  • The most common cause is acute tubular necrosis
  • Definition by KDIGO:
  1. Increase in Creatinine by 0.3 or more within 48 hours OR
  2. Increase in Cr to >1.5 x baseline, presumed to have occured within the prior 7 days
  3. Urine volume <0.5 mL/kg/hr x 6 hours


KDIGO Clinical Practice Guidelines, 2012.