UMEM Educational Pearls

Category: Toxicology

Title: Sumatriptan

Keywords: sumatriptan, myocardial infarction, migraine (PubMed Search)

Posted: 3/13/2008 by Fermin Barrueto, MD (Updated: 12/14/2019)
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  • A triptan that is a serotonin agonist
  • SQ administration better
  • High first pass effect and thus not effective often PO
  • Sulfhemoglobinemia see with high dose PO
  • Adverse Effects: MI and ischemia , CVA
  • Be wary with elderly, hx of CAD/CVA or hx of cocaine use