UMEM Educational Pearls

Mechanical Ventilation Pearls for Acute Ischemic Stroke

  • Patients with an acute ischemic stroke (AIS) may require intubation for various reasons.
  • Two main goals of mechanical ventilation in patients with an AIS are to maintain appropriate oxygen levels and tight control of PaCO2.
  • In terms of oxygenation:
    • Target normoxia
    • Administer O2 if the SpO2 is < 94%
    • Supplemental O2 is not recommended in non-hypoxic patients
  • In terms of CO2:
    • Target normocapnia
    • Hypercapnia increases the risk of intracranial hypertension
    • Hypocapnia can worsen cerebral perfusion

References

Robba C, et al. Mechanical ventilation in patients with acute ischemic stroke: from pathophysiology to clinical practice. Crit Care. 2019;23:388.