UMEM Educational Pearls

Category: Toxicology

Title: Black urine!

Keywords: Black urine, toxicological cause (PubMed Search)

Posted: 9/24/2020 by Hong Kim, MD, MPH
Click here to contact Hong Kim, MD, MPH



What medication ingestion can lead to black urine?


Black urine due to cresol intoxication | Postgraduate Medical Journal



There are many medical disorder and ingestion that can lead to change in urine colors. 

Black discoloration of urine can be caused by:


  • Alpha-methyldopa
  • Cresol
  • Iron
  • Laxatives (cascara, senna)
  • L-dopa
  • Methocarbamol
  • Metronidazole
  • Nitrofurantoin
  • Sorbitol

Medical condition

  • Alcaptonuria
  • Metastatic melanoma
  • Pophyria


Aycock, RD et al. Abnormal Urine Color. Southern Medical Journal 2012;105;43-47.


Black_urine.docx (115 Kb)