UMEM Educational Pearls

Category: Critical Care

Title: Sepsis and Mechanical Ventilation

Keywords: sepsis, mechanical ventilation, oxygen delivery (PubMed Search)

Posted: 1/13/2009 by Mike Winters, MD (Updated: 10/24/2020)
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Sepsis and Mechanical Ventilation

  • Essential components of the ED management of sepsis include early identification, antibiotics ASAP, fluid resuscitation, and maintaining adequate perfusion pressure.
  • If patients continue to have evidence of shock (i.e. high lactate) despite adequate fluids and/or pressors, strongly consider intubation, even in the patient without acute respiratory decompensation.
  • The respiratory muscles are avid consumers of oxygen and can use up to 50% of circulating O2.
  • Intubation and paralysis not only increase available O2 to vital organs, it can also augment cardiac output for patients with persistent septic shock.