UMEM Educational Pearls

Category: Neurology

Title: Lidocaine Toxicity

Keywords: lidocaine, lidocaine toxicity, seizure (PubMed Search)

Posted: 7/30/2009 by Aisha Liferidge, MD (Updated: 10/21/2021)
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  • Lidocaine toxicity typically manifests as central nervous system symptoms such as tongue numbness, tinnitus, visual disturbances, seizure, and cardiovascular depression.
  • The maximum dose of lidocaine without epinephrine is 5 mg/kg (4.5 mg/kg, to be exact) and 7 mg/kg for lidocaine with epinephrine.  The total maxiumum dose is 300 mg.