UMEM Educational Pearls

Category: Obstetrics & Gynecology

Title: Rhogam Dosing

Keywords: Rhogam, Pregnancy (PubMed Search)

Posted: 8/22/2009 by Michael Bond, MD (Updated: 11/27/2020)
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Rhogam Dosing:

Though most textbooks recommend Micro-Rhogram (50mcg) for woman that have miscarried and are less than 12 weeks gestation, you might find it a real challenge to get that dose from your pharmacy or blood bank.

The cost difference between microRhogram and Rhogam is minimal so most hospitals have decided to only stock full dose (300 mcg) Rhogam.  The full dose can be given to woman in their 1st trimester without any deleterious effects. 

Just remember if you are giving it as a result of a delivery you should order a Kleihauer-Betke test to determine if additional doses of Rhogam are needed.