UMEM Educational Pearls

Category: Endocrine

Title: Hyperparathyroidism

Keywords: hyperparathyroidism, hypercalcemia (PubMed Search)

Posted: 8/29/2009 by Michael Bond, MD (Updated: 9/5/2009)
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Hyperparathyroidism results in elevated PTH and typically results in elevated calcium levels (hypercalcemia). 

  • Primary hyperthryoidism is due to hyperfunction of the parathyroid glands, while secondary hyperthyroidism is a reaction of the parathyroid glands to hypocalcemia caused by another etiology, most commonly chronic renal failure. 
  • Tertiary hyperthyroidism is due to hyperplasia of the parathyroid glands due to loss of response to serum calcium levels and this too is seen in chronic renal failure

Though most cases are asymptomatic, symptomatic patients can present with:

  • weakness and fatigue
  • depression
  • aches and pains
  • decreased appetitie
  • constipation
  • polyuria and polydipsia
  • kidney stones
  • osteoporosis.

Treatment options to be discussed next week....Stay tuned.