UMEM Educational Pearls

MEWDS (Multiple Evanescent White Dot Syndrome)

  • A rare, unilateral, self-limiting inflammatory disease
  • Afflicts young women more than men in a 4:1 ratio.
  • Patients typically present complaining of
    • Sudden, painless, monocular decline in central acuity
    • Photopsias-- def. appearance as of sparks or flashes in retinal irritation
    • Dyschromatopsia-- def> disorder of color vision
    • Central/paracentral scotomas
  • Visual acuity usually in the  20/40-20/400
  • Fluorescein angiography of active lesions typically demonstrate a "wreath-like" hyperfluorescence of the white dots
  • Disease is usually self limited (resolves in weeks to months) with an excellent prognosis.
  • There are no known treatment options.

References

Multiple Evanescent White Dot Syndrome (MEWDS): 24 y.o. woman with one week duration of central scotoma, OD.
Presented by Sudeep Pramanik, MD, MBA, Hilary A. Beaver, MD http://webeye.ophth.uiowa.edu/eyeforum/cases/37-MultipleEvanescentWhiteDotSyndromeMEWDS.htm