UMEM Educational Pearls - Critical Care

Category: Critical Care

Title: Sepsis in Pregnancy

Posted: 2/17/2009 by Mike Winters, MD (Updated: 12/9/2019)
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Sepsis in Pregnancy

  • Sepsis in the setting of pregnancy is primarily the result of pelvic infections such as chorioamnionitis, endometritis, septic abortion, or urinary tract infection
  • In these patients, aerobic gram-negative rods (E. coli, Enterococci, Beta-hemolytic strep) are the principal etiologic agents
  • An empiric broad spectrum antibiotic regimen is ampicillin, gentamicin, and clindamycin (or metronidazole)

 

 

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Category: Critical Care

Title: Preventing VAP

Keywords: ventilator associated pneumonia, head of bed (PubMed Search)

Posted: 2/10/2009 by Mike Winters, MD (Updated: 12/9/2019)
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Ventilator Associated Pneumonia (VAP)

  • VAP is the leading cause of death among hospital acquired infections
  • VAP causes prolongation of mechanical ventilation, ICU/hospital length of stay, and adds about $40,000 to the patient's admission
  • As we care for more and more intubated patients for longer and longer periods of time, it is crucial to know some simple preventative measures we can do in the ED to reduce morbidity and mortality
  • In the absence of contraindications, elevate the head of the bed to 30-45 degrees for intubated patients
  • This is a simple, no cost intervention that has been shown to decrease the incidence of VAP

Category: Critical Care

Title: Sedation and Analgesia in Mechanical Ventilation

Keywords: sedation, analgesia, mechanical ventilation (PubMed Search)

Posted: 2/3/2009 by Mike Winters, MD (Updated: 12/9/2019)
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Sedation and Analgesia in Mechanical Ventilation

  • Mechanically ventilated patients routinely experience pain and anxiety from the presence of an endotracheal tube, ventilator strategies, placement of invasive catheters, surgical procedures, and even nursing procedures such as suctioning and repositioning.
  • Recent literature highlights that many of our vented patients received inadequate amounts of analgesia and anxiolysis
  • When giving anxiolytics and analgesics, focus first on analgesics
  • Patients given analgesics first, followed by anxiolytics, consistently achieve goals with less amounts of supplemental medications needed.

Category: Critical Care

Title: Sepsis and Pneumonia

Keywords: pneumonia, sepsis, severe sepsis, septic shock, mrsa, vancomycin (PubMed Search)

Posted: 1/28/2009 by Mike Winters, MD (Updated: 12/9/2019)
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Pneumonia and Sepsis

  • As we have discussed, one of the most important components in the ED management of sepsis is the administration of early and appropriate broad-spectrum antibiotics
  • Pneumonia remains one of the most common causes of sepsis in the US and worldwide
  • Given the steady rise in incidence of MRSA, remember to add vancomycin to your empiric treatment of patients with pneumonia and severe sepsis or septic shock

Category: Critical Care

Title: Anaphylaxis

Keywords: anaphylaxis, urticaria, angioedema, shock (PubMed Search)

Posted: 1/20/2009 by Mike Winters, MD (Updated: 12/9/2019)
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Clinical Manifestations of Anaphylaxis

  • Importantly, manifestations of anaphylaxis occur along a continuum and are dependent upon the type, route, and quantity of antigen exposure.
  • Cutaneous (90%), respiratory (40-70%), cardiovascular (30-35%), gastrointestinal (40%), neurologic (10%), ocular, and genitourinary symptoms can all be seen.
  • Include anaphylaxis in the differential of any patient with undifferentiated shock, as 10% will not manifest the cutaneous symptoms of urticaria and/or angioedema.

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Category: Critical Care

Title: Sepsis and Mechanical Ventilation

Keywords: sepsis, mechanical ventilation, oxygen delivery (PubMed Search)

Posted: 1/13/2009 by Mike Winters, MD (Updated: 12/9/2019)
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Sepsis and Mechanical Ventilation

  • Essential components of the ED management of sepsis include early identification, antibiotics ASAP, fluid resuscitation, and maintaining adequate perfusion pressure.
  • If patients continue to have evidence of shock (i.e. high lactate) despite adequate fluids and/or pressors, strongly consider intubation, even in the patient without acute respiratory decompensation.
  • The respiratory muscles are avid consumers of oxygen and can use up to 50% of circulating O2.
  • Intubation and paralysis not only increase available O2 to vital organs, it can also augment cardiac output for patients with persistent septic shock.

Category: Critical Care

Title: Fluids and ICH

Keywords: intracerebral hemorrhage, normal saline, hypertonic saline (PubMed Search)

Posted: 1/7/2009 by Mike Winters, MD (Updated: 12/9/2019)
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Intracerebral hemorrhage and fluid management

  • Isotonic fluids (0.9% saline) are the standard IV fluid for patients with ICH
  • The goal for fluid management is to maintain euvolemia with a urine output > 0.5 cc/kg
  • Importantly, 0.45% saline and dextrose containing IVFs should be avoided, as they can exacerbate cerebral edema and increase ICP
  • Hypertonic saline has become a popular aternative to normal saline in patients with significant perihematomal edema and mass effect
  • Goals when using hypertonic saline are to maintain serum osmolality between 300 - 320 mOsm/L and serum sodium between 150 - 155 mEq/L

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Category: Critical Care

Title: Blood Pressure and ICH

Keywords: blood pressure, intracerebral hemorrhage (PubMed Search)

Posted: 12/31/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Blood Pressure Control in ICH

  • Aggressive BP reduction after ICH is currently the focus of an ongoing NINDS study (ATACH Study)
  • Current literature recommends that extreme levels of BP after ICH be treated to reduce hematoma expansion
  • Mean arterial pressures (MAP) > 130 mmHg should be treated with continous IV medications
  • Current recommended medications include labetalol, esmolol, nicardipine, and fenoldopam
  • Nitroprusside is avoided by many given its tendency to increase ICP
  • Oral and sub-lingual medications are not indicated for immediate and precise BP control

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Category: Critical Care

Title: Hemofiltration

Keywords: renal replacement therapy, hemofiltration (PubMed Search)

Posted: 12/23/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Hemofiltration

  • Renal replacement therapy (RRT) involves the use of semipermeable membranes to remove fluid and toxic substances from the bloodstream
  • The basic methods of RRT are hemodialysis (HD) and hemofiltration (HF)
  • There have been a few cases in our ED in which our Renal consultants have used HF
  • Hemofiltration can remove large volumes of fluid (up to 3 Liters per hour)
  • Major advantages to HF: less likely to produce hypotension than HD, can remove larger molecules than HD
  • Disadvantages to HF: must be done continuously to provide effective dialysis, requires anticoagulation to maintain circuit patency, not well suited for hypotensive patients (requires a hydrostatic pressure gradient for solute clearance)

Category: Critical Care

Title: Critcal Care Billing Pearls

Keywords: Critical Care, reimburshment, billing (PubMed Search)

Posted: 12/20/2008 by Michael Bond, MD (Updated: 12/9/2019)
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Critical Care Billing Pearls:

 

Level RVU Medicare Commerical
99285    ED E/M, Level 5   4.71 $170 $304
99291    Critical Care, first hour 5.84 $211 $363



As the table shows Critical Care billing will earn you approximately 25% more with no additional overhead.  Critical care time must be at least 30 minutes, and the following procedures are included in the critical care code:   

  • Interpretation of ABG and labs
  • Interpretation of CXR
  • IV insertation
  • Transcutaneous pacing
  • Blood Draws
  • NG Tube placement

The following procedures are not bundled into critical care time, so they can be billed separately, therefore the time you spend doing these procedures can not be included in your total critical care time:

  • Central Line Placement
  • Lumbar Puncture
  • Intubation
  • Transvenious pacemaker placement
  • Arterial Line Placement
  • Chest Tube Placement
  • CPR


Remember critical care time does not need to be continuous but you need to be immediately available to the patient for the time to count.  You can not count time going off the floor to review an xray or CT, but this time can be counted if you do it in the immediate vacinity of the patient.

FINAL CAVEAT  To help your coders bill appropriately it helps to include a statement such as "Critical Care time XX minutes where I was directly involved in the care of this patient exclusive of all other separately billable procedures."

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Category: Critical Care

Title: Catheter Positioning

Keywords: central venous catheter (PubMed Search)

Posted: 12/16/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Catheter Positioning

  • Central venous catheters (CVC) inserted from the left side must make an acute angle downward when the enter the SVC from the innominate vein
  • CVCs that do no make this turn can end up with the tip pointing directly at the lateral wall of the SVC
  • CVCs in this position can cause perforation of the SVC
  • If the catheter tip is pointing at the SVC, then advance the catheter further down

Category: Critical Care

Title: Catheter Occlusion - Correction

Keywords: central venous catheter, tissue plasminogen activator (PubMed Search)

Posted: 12/9/2008 by Mike Winters, MD (Emailed: 12/11/2008) (Updated: 12/9/2019)
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My math may appear incorrect, however, I mistakenly left out that the protocol may be repeated once thereby giving up to a total of 4 mg of tPA.

Central Venous Catheter Occlusion

  • Many of us care for patients that present with pre-existing CVCs
  • Catheter occlusion is the most common complication associated with CVC
  • Thrombosis is the most common cause of obstruction of CVCs
  • Thrombosis is often be due to insoluble precipitates; meds such as diazepam, digoxin, phenytoin, and TMP-SMX can cause these precipitates
  • Local instillation of a thrombolytic agent (tPA) can be effective in restoring CVC patency
  • One protocol for use of tPA in CVC occlusion is to:
    • reconstitute a 50 mg vial with 50 mL sterile water (1 mg/mL)
    • draw up 2 mL in a 5 cc syringe and inject into the CVC - total tPA dose 2 mg
    • leave in place for approximately 2 hours
    • attempt to flush the CVC with a saline solution
  • If the catheter remains obstructed, a new CVC should be placed at a new site
  • The total drug dose in this regimen (4 mg) is too small to cause systemic thrombolysis

Category: Critical Care

Title: Hemodialysis Catheters

Keywords: hemodialysis catheters (PubMed Search)

Posted: 12/2/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Hemodialysis Catheters

Two weeks ago, we had a PEA arrest of a patient receiving HD.  A significant delay occurred in administering fluids and medications as a result of "no iv access".  Don't forget that in these situations you can use the hemodialysis catheter.

  • Typically these are double-lumen catheters in the IJ or femoral vein; one lumen carries blood to the HD machine and the other returns it to the patient
  • Importantly, each lumen is equivalent in diameter to an introducer catheter (8 French) - permitting rapid flow
  • Fluids and medications can be rapidly given through these catheters in code situations

Category: Critical Care

Title: SRMI ???

Keywords: stress related mucosal injury, histamine antagonists, proton pump inhibitors, sucralfate (PubMed Search)

Posted: 11/25/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Stress Related Mucosal Injury (SRMI)

  • As the length of stay for many of our critically ill patients continues to rise, it is important to think about some preventative therapies
  • SRMI is the term used to describe gastric mucosal erosions that occur in the critically ill
  • SRMI can be demonstrated in 75 - 100% of critically ill patients within 24 hours and can cause clinically apparent bleeding in up to 25%
  • Independent risk factors for SRMI include mechanical ventilation, coagulopathy, and a prior history of gastritis or peptic ulcer disease
  • Additional risk factors in our ED patient population include sepsis, hypotensive states, severe head injury, multisystem trauma, and renal failure
  • Typically an H2 antagonist is provided (i.e. ranitidine or famotidine).  Currently there is no evidence of superiority of PPIs over H2 antagonists in preventing SRMI
  • Pearl:  the best agent to give is probably sucralfate - there is a slightly higher incidence of bleeding compared to ranitidine; however, ranitidine is associated with a much higher incidence of nosocomial pneumonia.  The risk and mortality associated with nosocomial pneumonia in these patients outweighs the minimal risk of major hemorrhage associated with SRMI

Category: Critical Care

Title: Dopamine

Keywords: dopamine, hemodynamic medication, vasopressors (PubMed Search)

Posted: 11/18/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Dopamine in the ED

  • Recall that dopamine is an endogenous catecholamine that is a precursor for norepinephrine synthesis
  • Despite the popularity of norepinephrine, dopamine is still used by many EPs in the setting of septic shock
  • Dopamine produces progressive alpha-receptor stimulation at doses > 10 mcg/kg/min
  • Tachyarrhythmias (namely sinus tachycardia) is the predominant adverse effect
  • When selecting a vasopressor agent, be sure to check the HR.  If the patient is already tachycardic, the addition of dopamine will only worsen the tachycardia
  • Additional important adverse effects are increased intraocular pressure and delayed gastric emptying

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Category: Critical Care

Title: Seizures and the Critically Ill

Keywords: seizure, metabolic (PubMed Search)

Posted: 11/11/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Seizures in the Critically Ill

  • Seizures are a common complication in medical and surgical patients commonly arising from coexisting conditions associated with critical illness
  • Most seizures in the critically ill are generalized convulsions rather than focal
  • The majority of seizures occur in patients without a pre-existing history of seizure disorder
  • Common causes of seizures in the critically ill include sepsis, cardiovascular disease, metabolic abnormalities, medications, and drug intoxication/withdrawal
  • Metabolic abnormalities account for 30 -35% of causes
  • The most common metabolic abnormalities include hyponatremia, hypocalcemia, hypophosphatemia, uremia, and hypoglycemia
  • Be sure to check these labs in ICU patients with a seizure

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Category: Critical Care

Title: Auto-PEEP

Keywords: auto-peep, mechanical ventilation (PubMed Search)

Posted: 11/4/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Auto-PEEP in the non-COPD patient

  • In previous pearls we have discussed the concept of auto-peep in patients with expiratory flow limitation (asthma and COPD)
  • Unexpected auto-peep can also occur in up to 35% of patients without asthma or COPD
  • In these patients, auto-PEEP typically occurs with high minute ventilations (> 20 L/min) with shortened exhalation times or if exhalation is blocked (blocked ETT, exhalation valve, or PEEP valve)
  • Recall that auto-PEEP increases the work of breathing, worsens gas exchange, and can cause hemodynamic compromise 
  • Treatment of auto-PEEP can be as follows:
    • Change ventilator settings
      • increase expiratory time
      • decrease respiratory rate
      • decrease tidal volume
    • Reduce ventilatory demand
      • reduce anxiety, pain, fever with sedatives
    • Reduce flow resistance
      • large-bore ETT
      • frequent suctioning
    • Apply external PEEP

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Category: Critical Care

Title: Ventilator Therapy in ED Patients with ARDS

Keywords: PEEP, mechanical ventilation, ARDS (PubMed Search)

Posted: 10/28/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Ventilator Therapy for ED Patients with ARDS

  • As we manage critically ill patients for longer periods of time, it is likely that many of us will manage patients who develop ARDS
  • Current mortality for patients with ARDS ranges from 30-40%
  • ED treatment for patients with ARDS includes treating the inciting event, supportive critical care, and ventilator management
  • Current ventilator management in patients with ARDS includes:
    • avoiding alveolar overdistention (tidal volumes of 6 ml/kg)
    • maintaining FiO2 < 60% (mitigates oxygen toxicitty)
    • PEEP to prevent alveolar derecruitment (levels of 10-15 cm H2O)
    • permissive hypercapnea

Category: Critical Care

Title: Influenza and the Critically Ill

Keywords: influenza, zanamivir, oseltamivir (PubMed Search)

Posted: 10/21/2008 by Mike Winters, MD (Updated: 12/9/2019)
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 Influenza and the Critically Ill

  • It is that time of year again to be vigilant for cases of influenza
  • Influenza is not benign and causes > 40,000 deaths per year and is the 7th leading cause of death in the US
  • In the critically ill, the most severe disease occurs in patients > 65 and those with underlying cardiopulmonary disease
  • Critically ill patients with influenza can present with fever, cough, bilateral interstitial infiltrates, hypoxemia, and leukopenia
  • Other serious complications include myocarditis, encephalitis, and Reye syndrome
  • Amantadine and rimantadine should no longer be used, as the resistance has risen to > 90% in some populations
  • Oseltamivir (PO) and zanamivir (powder/inhalation) are the approved neuraminidase inhibitors; both decrease the severity and duration of illness; should be given as early as possible, preferably within 36 hours

 

 

 

 

 

 

 

 

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Category: Critical Care

Title: Tension Gastrothorax?

Keywords: gastrothorax, pneumothorax (PubMed Search)

Posted: 10/8/2008 by Mike Winters, MD (Updated: 12/9/2019)
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Tension gastrothorax?

  • Tension gastrothorax is a life threatening condition characterized by herniation of the stomach through a defect in the diaphragm with compression of the mediastinal contents
  • Although many cases occur in pediatric patients (secondary to congenital defects), adults with a history of diaphragmatic injury are at risk (also patients with a type III or IV hiatal hernia)
  • The clinical presentation is the same as a tension pneumothorax - hypotension, tachycardia, hypoxia, JVD, and decreased breath sounds
  • CXR appearance can be very similar to tension pneumothorax, however, the treatment is substantially different
  • Needle decompression and tube thoracostomy are contraindicated, as this may cause visceral perforation
  • The treatment of choice is NGT (or OGT) decompression followed by surgical repair

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