UMEM Educational Pearls

Category: Pediatrics

Title: Mycoplasma pneumoniae Induced Rash and Mucositis (MIRM)

Posted: 3/30/2018 by Rose Chasm, MD (Updated: 4/25/2024)
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Stevens-Johnsons like rash and mucositis
Most common in children and adolescents, with a mean age of 12 years old
More common in males than females, 2:1
Prodromal symptoms of cough, fever, and malaise precede
Mucositis far out of proportion to body rash, 90% vs 10%
Mucositis is primarily oral > ocular > genital in distribution, and can be severe
Body rash may involve palms and soles
Complications: dehydration, GIB, epiglottitis, blindness, pericardial effusion
Testing: PCR nasal wash/BAL; agglutination assays IgM/IgG
Treatment: azithromycin and supportive care; occasionally steroids; rarely IVIG
Unlike Stevens-Johnsons, prognosis is good.