UMEM Educational Pearls

The incidence of pediatric syncope is common with 15%-25% of children and adolescents experiencing at least one episode of syncope before adulthood. Incidence peaks between the ages of 15 and 19 years for both sexes.

Although most causes of pediatric syncope are benign, an appropriate evaluation must be performed to exclude rare life-threatening disorders. In contrast to adults, vasodepressor syncope (also known as vasovagal) is the most frequent cause of pediatric syncope (61%–80%).  Cardiac disorders only represent 2% to 6% of pediatric cases but account for 85% of sudden death in children and adolescent athletes.  17% of young athletes with sudden death have a history of syncope.

Key features on history and physical examination for identifying high-risk patients include exercise-related symptoms, a family history of sudden death, a history of cardiac disease, an abnormal cardiac examination, or an abnormal ECG.

Pediatric Dysrhythmias that can cause syncope in children:
- Congenital long QT
- Brugada syndrome
- Catecholaminergic polymorphic VT
- Wolff-Parkinson-White syndrome (WPW)
- Congenital short QT
- Hypertrophic Cardiomyopathy (HCM)
- Arrythmogenic RV dysplasia.
 
 
Reference:
Fischer JW, Cho CS. Pediatric syncope: cases from the emergency department. Emerg Med Clin North Am. 2010 Aug; 28(3):501-16.


Intubated patients may occasionally meet certain criteria for extubation while in the Emergency Department. Extubation is not without its risk, however, as up to 30% of patients have respiratory distress secondary to laryngeal and upper airway edema, with some patients requiring re-intubation.

Prior to extubation, Intensivists use a brief “cuff-leak” test (deflation of the endotracheal balloon to assess the presence or absence of an air-leak around the tube) to indirectly screen for the presence of upper airway edema and ultimately the risk of re-intubation. The cuff-leak test is performed by deflating the endotracheal balloon followed by one or more of the following maneuvers:

  • Using the ventilator to measure the difference between inspired and expired tidal volumes; if there is a difference in the measured volumes, then air is “leaking” around the endotracheal tube, implying minimal airway edema.
  • Auscultation for an air “leak” around the tube during mechanical ventilation; auscultation of a leak implies that air is passing around the tube and minimal airway edema is present.
  • Disconnecting the patient from the ventilator and occluding the endotracheal tube during spontaneous breathing; auscultation of a leak implies that there is air passing around the tube and minimal airway edema is present.

Ochoa et al. performed a systematic review to determine the accuracy of the “cuff-leak” test to predict upper airway edema prior to extubation. The authors concluded that a positive cuff-leak test (i.e., absence of an air-leak) indicates an elevated risk of upper airway obstruction and re-intubation. A negative cuff-leak test (i.e., presence of an air-leak), however, does not reliably exclude the presence of upper airway edema or the need for subsequent re-intubation.

Bottom line: No test prior to extubation reliably predicts the absence of upper airway edema. Patients extubated in the Emergency Department require close observation with airway equipment located nearby.

 

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Guide-wires can be challenging to dispose of after central-line insertion because they are difficult to keep on the field, hard to place in the sharps box, and can splash nearby observers.

Click here for this little guide-wire disposal trick.

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Title: Brugada Syndrome

Category: Cardiology

Keywords: Brugada syndrome (PubMed Search)

Posted: 9/23/2012 by Semhar Tewelde, MD
Click here to contact Semhar Tewelde, MD

 

Autosomal dominant inherited arrhythmic disorder characterized by mutation in sodium-channels
Arrhythmic events are often observed at rest or while asleep, resulting in VF and SCD
Diagnostic criteria consists of 2 parts: (1) ECG abnormalities (2) clinical characteristics
A. ECG abnormalities: incomplete or complete RBBB in right precordial leads (V1-V2) w/
    Type I coved-type ST segment elevation and negative T wave 
    Type II saddle-back ST segment elevation followed by a positive or biphasic T wave 
    Type III ST segment elevation without meeting criteria for type I or II variants
B. Clinical characteristics: hx of VT/ VF, family hx of SCD or abnormal ECG, agonal respirations during sleep, or inducible VT/VF during EP study

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Title: SLAP lesions

Category: Orthopedics

Keywords: Shoulder, biceps, cartilage tear (PubMed Search)

Posted: 9/22/2012 by Brian Corwell, MD (Updated: 11/19/2013)
Click here to contact Brian Corwell, MD

SLAP tear/lesion – Superior labral tear anterior to posterior

Glenoid labrum – A rim of fibrocartilaginous tissue surrounding the glenoid rim, deepening the “socket” joint and is integral to shoulder stability

http://www.orthospecmd.com/images/shoulder_labral_tear_anat_02.jpg

Injury is most commonly seen in overhead throwing athletes

Or from a fall on the outstretched hand, a direct shoulder blow or a sudden pull to the shoulder

Sx’s:  A dull throbbing pain, a “catching” feeling w/ activity. Some describe clicking or locking of the shoulder. May also include nighttime symptoms. Pain is located to the anterior, superior portion of the shoulder.

Athletes may describe a significant decrease in throwing velocity

http://sitemaker.umich.edu/fm_musculoskeletal_shoulder/o_brien_s_test



Title: Pediatric intubation (submitted by Danya Khoujah, MBBS)

Category: Pediatrics

Keywords: premedication, RSI, ventilator, high flow nasal cannula (PubMed Search)

Posted: 9/21/2012 by Mimi Lu, MD
Click here to contact Mimi Lu, MD

When intubating an infant, a few key points need to be kept in mind:
- Remember that the narrowest point is the cricoid, so even if the ETT passes the cords it might still not pass through the cricoid itself.
- Remember premedication with atropine is recommended in all children less that 1 year old and in those less than 5 years old when using succinylcholine. It is used to prevent reflex bradycardia and high ICP and to decrease secretions. The dose is 0.02 mg/kg IV, with a minimum of 0.1 mg and a max of 0.5 mg. Give it 2 full minutes before the start of intubation.
- Remember that succinylcholine is contraindicated in neuromuscular disease (including an undiagnosed myopathy). A slightly higher dose (2mg/kg) may need to be used in infants (compared to 1-1.5mg/kg in adults and older children).  
- Pressure control mode is preferred over volume control (VC) setting in peds, because VC tends to overestimate how much volume it's delivering, therefore delivering inadequate ventilation.
- Remember your alternatives: High Flow Nasal cannula (HFNC) can be used in infants with respiratory distress to avoid intbation. One study showed that is decreased intubation rates by 68% in respiratory distress due to bronchiolitis
 
References:
1. Santillanes G, Gausche-Hill M. Pediatric Airway Management. Emerg Med Clin N Am 26 (2008) 961–975
2. Bledsoe G H, Schexnayder S M. Pediatric Rapid Sequence Intubation A Review. Ped Emerg Care 20 (2004) 339-344


Just when you think buying organic protects you from chemicals and pesticide, along comes the studies detecting arsenic in rice products and specficially in organic foods with brown rice organic sweetener. An organic toddler milk formula reportedly had 6x EPA standards for safe drinking water limit.

The more toxic arsenic is the inorganic arsenic which can cause neuropathy but after chronic exposure can cause a classic arsenic keratosis - see attached pic. The inorganic is seen commonly in seafood and is more easily excreted by the body. Unfortunately, in the study referenced here, inorganic As was the predominant type.

 

 

 

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The Lung Transplant Patient in Your ED

  • The number of lung transplant recipients is increasing.  With improved immunosuppressant medications, pts are living longer.  In fact, the 5-yr survival rate is now approximately 60%.
  • When evaluating a lung transplant pt who is < 1 yr following transplant, think about acute rejection and infection
  • Acute rejection occurs in up to 40% of pts, can present with cough, SOB, malaise, or hypoxia, and is treated with high-dose corticosteroids.
  • Infection
    • Bacterial infections usually occur in the early stages following transplant, with Pseudomonas the predominant organism
    • CMV is the most common organism affecting up to 33% of pts during the first year after transplant

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Question

27 year-old woman with AIDS presents complaining of a painful, puritic, and papular rash. What's the diagnosis?

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Pericarditis is based on clinical diagnosis; typically two of four criteria are found (pleuritic chest pain, pericardial rub, diffuse ST-segment elevation, and pericardial effusion).

Most common cause of pericardial disease in the world is tuberculosis vs. idiopathic or viral causes in developed countries.

Treatment of pericarditis should be targeted at the cause.

NSAIDs and newer literature suggest colchicine are first line for most cases, except in systemic inflammatory diseases or pregnancy where low dose prednisone is often the preferred agent.

Most causes of pericarditis have a good prognosis and are self-limited.

The most feared complication is constrictive pericarditis.

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Lactate levels help to confirm septic arthritis but what about bacterial meningitis.  As reported in the daily electronic ACEP newsletter a small study of 45 patients showed that all patients with a confirmed diagnosis of bacterial meningitis had a CSF lactate level > 3.5 mmol/L.  Therefore, it might be true that viral meningitis will only have  CSF lactate levels < 3.5 mmol/L. 

With only 45 patients, this finding is clearly not ready for Prime Time but consider adding it to your next CSF study so more data can be collected on the utility of this test.

The story as seen in ACEP eNews on September 14th, 2012 is:

CSF Levels Of Lactate May Be A Marker Of Viral Versus Bacterial Meningitis.

MedPage Today (9/14, Gever) reports, "Cerebrospinal fluid (CSF) levels of lactate were a perfect marker of viral versus bacterial meningitis in a small study, a researcher reported" at the Interscience Conference on Antimicrobial Agents and Chemotherapy. Researchers found that, "among 45 adults in whom the etiology of meningitis was microbiologically confirmed, all those with CSF lactate levels above 3.5 mmol/L had the bacterial form, whereas every patient with lower levels had viral meningitis."



Title: Night Terrors

Category: Pediatrics

Posted: 9/15/2012 by Rose Chasm, MD (Updated: 11/26/2024)
Click here to contact Rose Chasm, MD

  • sleep disruption silimar to a nightmare, but much more dramatic most often between 4-12 years
  • sudden fear reaction which occurs during the transition to and from deep non-REM sleep while nightmares occur during REM sleep
  • occurs 2-3 hours after falling asleep when the child suddenly awakens in distress and may thrash about, scream, cry
  • child returns to sleep with no memory of the event the following morning
  • often occurs when a child is stressed, overtired, on new medication, or sleeping in a new environment
  • do not awaken the child during the event but rather allow them to calm on their own


Title: Cyanide from Smoke Inhalation in Enclosed-Space Fires

Category: Toxicology

Keywords: cyanide, smoke inhalation, enclosed-space fire, carbon monoxide (PubMed Search)

Posted: 9/7/2012 by Bryan Hayes, PharmD (Updated: 9/13/2012)
Click here to contact Bryan Hayes, PharmD

Carbon monoxide (CO) and hydrogen cyanide (HCN) are two of the main gases causing injury and death from smoke inhalation in fire victims. During the first phase of a fire, and prior to depletion of oxygen reserves and subsequent production of CO, formation of HCN from the thermal breakdown of nitrogen-containing materials may be the primary cause of lethal poisoning in an enclosed-space fire.

A recent, retrospective, observational study from Poland assessed the prevalence of toxic HCN exposure in victims of enclosed-space fires.

Important findings:

  • Of the 285 patients who died, 169 (59%) had detectable cyanide blood levels. 82% also had elevated carboxyhemoglobin (COHb) levels.
  • Of the 40 patients who survived, 20 (50%) had detectable cyanide blood levels. All 20 had elevated COHb levels.

Conclusion: The high prevalence of coincident HCN concentrations and COHb levels in victims of enclosed-space fires emphasises the need to suspect HCN as a co-toxin in all persons rescued from fire who show signs and symptoms of respiratory distress.

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Question

40 year-old male with severe uncontrolled hypertension presents with altered mental status (head CT below). The CXR is from the same patient. What's the connection?

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Question

40 year-old male with severe uncontrolled hypertension presents with altered mental status. Head CT is shown here. Name three common anatomic locations generally seen for non-traumatic intracerebral hemorrhage. 

 

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Title: blood pressure and organ perfusion

Category: Cardiology

Keywords: mean arterial pressure, blood pressure (PubMed Search)

Posted: 9/9/2012 by Amal Mattu, MD (Updated: 11/26/2024)
Click here to contact Amal Mattu, MD

Which patient has a better blood pressure, the patient with a blood pressure of 110/40 or the patient with a blood pressure of 90/60?

 

Mean arterial pressure (MAP) is generally considered to be the organ perfusion pressure in an individual. Because MAP requires an inconvenient calculation, we've all been taught...misled perhaps...into focusing on systolic blood pressure (SBP) as a marker of how well-perfused a patient is, and we tend to ignore the diastolic blood pressure (DBP).

 

It's important to remember, however, that we spend most of our lives in diastole, not systole. As a result, our organs spend more time being perfused during diastole than systole. The MAP takes this into account: MAP = (SBP + DBP + DBP)/3. DBP is more important than SBP!

 

So which patient is perfusing his vital organs better, the one with a BP of 110/40 or the one with a BP of 90/60? Do the MAP calculation...90/60 is better than 110/40!

 

Pay more attention to those diastolic BPs!



Title: Apprehension test for patellar dislocation

Category: Orthopedics

Keywords: Apprehension test, patellar dislocation, (PubMed Search)

Posted: 9/8/2012 by Brian Corwell, MD
Click here to contact Brian Corwell, MD

Apprehension test for patellar dislocation

 

Test is used to access for the possibility of a patellar dislocation, prior to evaluation, now spontaneously reduced.                                                   

Similar to the shoulder apprehension test

Designed to place the patella in a position of imminent subluxation or dislocation

http://mulla.pri.ee/Kelley%27s%20Textbook%20of%20Rheumatology,%208th%20ed./HTML/f4-u1.0-B978-1-4160-3285-4..10042-7..gr16.jpg

http://www.youtube.com/watch?v=9AJxcbd9g8A

 

Place the knee in 20 - 30 degrees of flexion with the quadripces relaxed. Grasp the patella and attempt to place lateral directed stress.

If the patella is about to dislocate, the patient will experience apprehension due to the familiar pattern of dislocation, report the laxity and resist further motion by contracting the quadriceps



Title: Evaluating the Cervical Spine in Pediatric Trauma

Category: Pediatrics

Keywords: cervical spine, trauma, pediatrics (PubMed Search)

Posted: 9/7/2012 by Lauren Rice, MD
Click here to contact Lauren Rice, MD

 

 

Ligamentous laxity is increased in children and ligamentous injury is more common than fractures.

If fractures occur, they are more likely to be in the upper cervical spine in infants and the lower cervical spine in older children.

Pseudosubluxation:  physiologic subluxation between C2-3 and C3-4 may exist until age 16 years

 

 

Screening Assessment/Clearance for Verbal Children

-Midline C-spine tenderness?

-Pain with active motion?

-Altered level of alertness?

-Evidence of intoxication?

-Focal neurological deficit?

-Distracting painful injury?

-High impact injury?

 

Screening Assessment/Clearance for Pre-Verbal Children

-Neurological assessment of basic reflexes

-Response to painful stimuli

-Equal movements of all extremities

-Response to sound (eye tracking)

-Extremity strength and resistance

-Palpate posterior C-spine (observe for facial grimace)

-Feel for step-offs, deformities

-Verify full range of motion of neck (may need to be creative) 

-Repeat neurological assessment 

 

If concern arises on screening assessment, keep child in hard cervical collar and image (may start with x-ray and progress to CT if still concerned and x-rays negative).

If imaging negative, but persistent suspicion based on neurological deficits consider SCIWORA (Spinal Cord Injury WithOut Radiographic Abnormality) which exists in up to 50% of children with cervical cord injury, and may require MRI to further identify injury.



Title: Intermediate Syndrome

Category: Toxicology

Keywords: organophosphates, intermediate syndrome (PubMed Search)

Posted: 9/6/2012 by Ellen Lemkin, MD, PharmD
Click here to contact Ellen Lemkin, MD, PharmD

 

  • Exposure to organophosphates can lead to “intermediate syndrome.”
  • It is a syndrome characterized by weakness of neck flexors and proximal limbs, cranial nerve palsies, and respiratory muscle weakness, which can lead to respiratory paralysis.
  • It follows acute cholinergic syndrome and precedes a delayed neuropathy, thus it is an “intermediate syndrome,” typically developing 24-96 hours post exposure.
  • The pathophysiology of IMS remains unclear.
  • Serum cholinesterase levels and electrophysiological studies are helpful in confirming the diagnosis.
  • With supportive therapy, including artificial ventilation, complete recovery occurs within 5-18 days.


Right Heart Failure in the Critically Ill

  • In its most simplistic form, right heart failure (RHF) is due to either to right ventricular contractile dysfunction or elevated right ventricular afterload.
    • Primary causes of RV contractile dysfunction include: coronary ischemia, sepsis, drug toxicity, and acute pulmonary hypertension
    • Primary causes of increased RV afterload include: LV dysfunction, venous thromboembolism, hypoxic pulmonary vasoconstriction, and lung injury
  • Management of the patient with RHF centers on identifying and treating reversible causes, optimizing preload, inotropes, and possible implantation of a right ventricular assist device.
  • Importantly, excessive volume loading can worsen RV contractile function, increase RV dilatation, and impair LV output and systemic perfusion.
  • Consider early use of inotropic agents, such as dobutamine, in critically ill patients with RHF.

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